Results 91 to 100 of about 1,122,324 (312)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The present situation and advance of red blood cell transfusion triggers

open access: yesZhongguo shuxue zazhi
In clinical practice, red blood cell infusion needs to be based on the patient′s hemoglobin level. However, different guidelines recommend different thresholds for red blood cell infusion and the timing of blood transfusion initiation is still ...
Yuye CHEN   +4 more
doaj   +1 more source

Towards an Innovative Sensor in Smart Capsule for Aerial Drones for Blood and Blood Component Delivery. [PDF]

open access: yesMicromachines (Basel), 2022
Liu R   +5 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Plasma Fibrinogen as a Predictor of Perioperative-Blood-Component Transfusion in Major-Nontraumatic-Orthopedic-Surgery Patients: A Cohort Study. [PDF]

open access: yesDiagnostics (Basel), 2023
Pagnussatt Neto E   +5 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Retrospective Analysis of Reasons for Discarding Whole Blood and Blood Components at Tertiary Care Hospital Blood Bank in South Gujarat

open access: yesNational Journal of Community Medicine, 2017
Introduction: Blood transfusion is an integral part of medical practice. Proper utilization of blood and its components with minimal wastage is necessary because each unit of blood is precious.
Niketa Roy, Ankita Shah
doaj  

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