Results 91 to 100 of about 2,005,926 (345)

Stored blood has compromised oxygen unloading kinetics that can be normalized with rejuvenation and predicted from corpuscular side-scatter

Haematologica, 2021
Killian Donovan, Athinoula Meli, Francesca Cendali, Kyung Chan Park, Rebecca Cardigan, Simon Stanworth, Stuart McKechnie, Angelo D’Alessandro, Peter A. Smethurst, Pawel Swietach   +9 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Effects of Hematocrit of the Sealed Blood on the Leakage Characteristics of Blood Cell Component and Plasma Component in a Mechanical Seal

Tribology Online, 2016
The purpose of this study is to find out the effects of hematocrit of the sealed blood on the leakage characteristics of blood cell components and plasma components in a mechanical seal, which separates blood from cooling water.
Jun Tomioka, Mikiko Oyabu, Norifumi Miyanaga   +2 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Transverse NMR relaxation in magnetically heterogeneous media

, 2008
We consider the NMR signal from a permeable medium with a heterogeneous Larmor frequency component that varies on a scale comparable to the spin-carrier diffusion length.
Abrikosov, Bandettini, Bauer, Bauer, Belliveau, Benga, Bjørnerud, Crooker, D.S. Novikov, Dickinson, Dyakonov, Gillis, Glasel, Jackson, Jensen, Jensen, Kennan, Kikkawa, Kikkawa, Kiselev, Kiselev, Kiselev, Kiselev, Kuchel, Kuchel, Kwong, Landau, Lau, Menon, Ogawa, Ogawa, Salis, Sukstanskii, Sukstanskii, Sukstanskii, Torrey, V.G. Kiselev, Vlaardingerbroek, Waldeck, Yablonskiy   +39 more
core   +1 more source

Analysis on discard of blood and its products with suggested possible strategies to reduce its occurrence in a blood bank of tertiary care hospital in Western India

Global Journal of Transfusion Medicine, 2017
Background: Blood is precious and should be utilized judiciously with minimal wasting. By analyzing the data and the reasons for discard, the blood transfusion service can develop plans to evaluate causes that lead to discard of blood and its components ...
Ashishkumar Nathabhai Kanani, Jitendra H Vachhani, Spruha K Dholakiya, Shweta B Upadhyay   +3 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Heuristic model in joint EEG-fMRI analysis [PDF]

, 2015
This work deals with the joint EEG-fMRI analysis based on the heuristic model. There is described principle of the heuristic model which assumes that the BOLD (blood oxygen level depend) signal measured by fMRI (functional magnetic resonance imaging) is ...
Janeček, D.
core  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Blood component separation in straight microfluidic channels. [PDF]

Biomicrofluidics, 2023
Lee LM, Bhatt KH, Haithcock DW, Prabhakarpandian B.   +3 more
europepmc   +1 more source