Results 111 to 120 of about 1,122,324 (312)

Herniation of blood bag during component preparation

Asian Journal of Transfusion Science, 2023
John Gnanaraj, Esha Toora, Abhishekh Basavarajegowda   +2 more
doaj   +1 more source

Whole blood transfusion versus component therapy in trauma resuscitation: a systematic review and meta‐analysis [PDF]

, 2020
Ellen Crowe, Stacia M. DeSantis, Austin Bonnette, Jan O. Jansen, José‐Miguel Yamal, John B. Holcomb, Claudia Pedroza, John A. Harvin, Marisa B. Marques, Elenir B.C. Avritscher, Henry E. Wang   +10 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Strategy of Blood Component Production for Transfusion: The Best Method for Developing Countries

Sokoto Journal of Medical Laboratory Science, 2017
The current standard blood processing practice is to split blood into its various components usually done by a process such as aphaeresis or whole blood donation involving centrifugation and filtration.
Bukar Alhaji, Digban Kestar Awharentomah, Obi Simon Osita, Medugu Jessy Thomus, Waziri Gimba, Ladu Adama Isa, Peyou Bachir, Abja Usman Medugu, Olaniyan Matthew Folaranmi and Jeremiah Zaccheaus Awortu.
doaj  

Making every drop count: reducing wastage of a novel blood component for transfusion of trauma patients. [PDF]

BMJ Open Qual, 2021
McCullagh J, Proudlove N, Tucker H, Davies J, Edmondson D, Lancut J, Maddison A, Weaver A, Davenport R, Green L.   +9 more
europepmc   +1 more source

Ambient Particle Components and Newborn Blood Pressure in Project Viva [PDF]

, 2020
Antonella Zanobetti, Brent A. Coull, Heike Luttmann‐Gibson, Lenie van Rossem, Sheryl L. Rifas‐Shiman, Itai Kloog, Joel Schwartz, Emily Oken, Jennifer F. Bobb, Petros Koutrakis, Diane R. Gold   +10 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Reducing the risk of transfusion-transmitted infectious disease markers in blood and blood component donations: Movement from remunerated to voluntary, non-remunerated donations in Lithuania from 2013 to 2020. [PDF]

PLoS One, 2022
Kalibatas V, Kalibatienė L.
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Current Understanding of the Relationship between Blood Donor Variability and Blood Component Quality. [PDF]

Int J Mol Sci, 2021
Hadjesfandiari N, Khorshidfar M, Devine DV.   +2 more
europepmc   +1 more source