Results 291 to 300 of about 11,633,289 (338)

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Nationwide Survey of Atopic Myelitis and Plexin D1‐Immunoglobulin G‐Related Pain

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To elucidate the features of plexin D1‐immunoglobulin (Ig)G‐associated neuropathic pain and its relationship to atopic myelitis (AM) in a nationwide Japanese survey. Methods A preliminary survey questionnaire was sent to 1574 selected departments (neurology and pediatrics/pediatric neurology) to explore the numbers of AM and plexin ...
Jun‐ichi Kira, Xu Zhang, Takayuki Fujii, Mikio Mitsuishi, Miho Ushijima, Sato Yoshidomi, Ayako Sakoda, Tomohiro Imamura, Satoshi Kuwabara, Noriko Isobe, Yuri Nakamura   +10 more
wiley   +1 more source

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Whole Blood Versus Conventional Blood Component Massive Transfusion Protocol Therapy in Civilian Trauma Patients

The American surgeon, 2021
Background Military data demonstrating an improved survival rate with whole blood (WB) have led to a shift toward the use of WB in civilian trauma. The purpose of this study is to compare a low-titer group O WB (LTOWB) massive transfusion protocol (MTP ...
Janet S. Lee, Abid D. Khan, F. Wright, R. McIntyre, W. Dorlac, C. Cribari, Valerie Brockman, Stephanie Vega, Jessica M. Cofran, T. Schroeppel   +9 more
semanticscholar   +1 more source

Thromboelastography‐Guided Blood Component Use in Patients With Cirrhosis With Nonvariceal Bleeding: A Randomized Controlled Trial

Hepatology, 2020
Thromboelastography (TEG) provides a more comprehensive global coagulation assessment than routine tests (international normalized ratio [INR] and platelet [PLT] count), and its use may avoid unnecessary blood component transfusion in patients with ...
M. Kumar, J. Ahmad, R. Maiwall, A. Choudhury, M. Bajpai, Lalita Mitra, V. Saluja, Prashant Mohan Agarwal, C. Bihari, S. Shasthry, A. Jindal, A. Bhardwaj, G. Kumar, S. Sarin   +13 more
semanticscholar   +1 more source

Design approach of solid-core photonic crystal fiber sensor with sensing ring for blood component detection

Journal of Nanophotonics, 2019
. The solid-core photonic crystal fiber (PCF) sensor with circular sensing ring has been proposed for biochemical detection. Finite-element method-based numerical technique has been applied to solve Maxwell’s equations with perfect matched boundary ...
Veerpal Kaur, Surinder Singh
semanticscholar   +1 more source

The Las Vegas mass shooting: An analysis of blood component administration and blood bank donations

Journal of Trauma and Acute Care Surgery, 2019
BACKGROUND The deadliest mass shooting in modern United States history occurred on October 1, 2017, in Las Vegas, killing 58 and overwhelming hospitals with more than 600 injured.
M. Lozada, Stephanie Cai, Marissa Li, S. L. Davidson, Justin Nix, Glenn Ramsey   +5 more
semanticscholar   +1 more source

Dynamic Spectrum for noninvasive blood component analysis and its advances

Applied spectroscopy reviews (Softcover ed.), 2018
Noninvasive blood component analysis by spectroscopy has broad prospects that based on Dynamic Spectrum (DS) can effectively suppress the influences of individual differences (such as skin, muscle, fat) and the variations of measurement conditions, which
Yuyu Wang, Gang Li, Hui-quan Wang, M. Zhou, Ling Lin   +4 more
semanticscholar   +1 more source