Blood component therapy in trauma
Background: Injury is the leading cause of life years lost, and hemorrhage is responsible for 40% of all trauma deaths and is commonly associated with coagulopathy, necessitating the use of blood and blood components.
Ambuja Kantharaj, Shivaram Chandrashekar
doaj +1 more source
Effects of Accelerated Rehabilitation Exercise on the Senior Fitness Test (SFT), Isometric Muscle strength, and Blood Profile in Older Adult Women with Degenerative Knee Osteoarthritis [PDF]
PURPOSE This study aimed to investigate the effects of accelerated rehabilitation exercise on physical fitness, lower extremity isometric strength, and blood variables in older adult women diagnosed with degenerative osteoarthritis. METHODS A total of 29
Ju-ri Lee+3 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Blood Components for Hemostasis [PDF]
We present an overview of revised indications and doses for routinely transfused blood components. Targeted blood component therapy is one of the earliest models of personalized medicine, striving to achieve the tenets of the right dose at the right time for the right reason to the right patient.
Glenn Ramsey, Jun Teruya
openaire +3 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Mathematical modelling of ethanol metabolism in normal subjects and chronic alcohol misusers [PDF]
The time course of ethanol disappearance from the blood has been examined in normal males and females and in alcohol misusers. Blood alcohol estimations were made over a period of 3 hr, following an oral dose of ethanol (0.8 g/kg body weight ...
Maini, P. K.+5 more
core
Improved correction for the tissue fraction effect in lung PET/CT imaging [PDF]
Recently, there has been an increased interest in imaging different pulmonary disorders using PET techniques. Previous work has shown, for static PET/CT, that air content in the lung influences reconstructed image values and that it is vital to correct ...
Cuplov, V+6 more
core +3 more sources
Effects of palm kernel cake (PKC) on growth performance, blood components and liver histopathology of sex reversed red tilapia (Oreochromis niloticus) [PDF]
Effects of Palm Kernel Cake (PKC) on growth performance, blood components and liver histopathology of sex- reversed red tilapia Oreochromis niloticus were studied using seven isocaloric diets (3400 kCal/ kg) containing different levels of protein and PKC.
Sukasem, N., Ruangsri, J.
doaj
Burden of transfusion transmissible viral infections among blood donors at a tertiary care referral teaching hospital in South India [PDF]
Background: Blood serves as a vehicle for transmission of blood-borne pathogens including human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV).
Suresh B+3 more
doaj +1 more source