Inspiratory muscle training enhances pulmonary O2 uptake kinetics and high-intensity exercise tolerance in humans [PDF]
Fatigue of the respiratory muscles during intense exercise might compromise leg blood flow, thereby constraining oxygen uptake (VO2) and limiting exercise tolerance. We tested the hypothesis that inspiratory muscle training (IMT) would reduce inspiratory
Bailey, SJ+5 more
core +2 more sources
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
The usage of blood components in obstetrics [PDF]
Major obstetric hemorrhage remains the leading cause of maternal morbidity and mortality worldwide. Even though blood transfusion may be a life-saving procedure, an inappropriate usage of blood products in obstetric emergencies especially in cases of massive bleeding is associated with increased morbidity and risk of death.
Adukauskienė, Dalia+4 more
openaire +2 more sources
Combining indoor residual spraying with chlorfenapyr and long-lasting insecticidal bed nets for improved control of pyrethroid-resistant Anopheles gambiae: an experimental hut trial in Benin. [PDF]
BACKGROUND: Neither indoor residual spraying (IRS) nor long-lasting insecticidal nets (LLINs) are able to fully interrupt transmission in holoendemic Africa as single interventions.
Akogbeto, M+7 more
core +4 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Early contingentnegative variation of the EEG and attentional flexibility are reduced in hypotension [PDF]
This study explored the question as to whether hypotension is related to decreased attentional performance and reduced cortical activation. A total of 50 females aged 19 44 years participated in the study. Attentional performance was assessed using three
Duschek, Stefan+4 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Human Blood Component Vaccinia Virus Neutralization Assay
Many therapeutic viruses, such as oncolytic viruses, vaccines, or gene therapy vectors, may be administered by the intravenous route to maximize their delivery to target tissues.
Laura Evgin, John Bell
doaj +1 more source
Introduction: The specific impact on calcium dynamics after non-massive blood transfusions remains relatively unexplored. This study aimed to compare pre- and post-transfusion calcium levels in patients receiving blood and blood product in the emergency
Halil Emre Koyuncuoglu+3 more
doaj +1 more source
Blood and Blood Components: From Similarities to Differences [PDF]
Blood transfusion is made possible because, in most countries and organizations, altruistic individuals voluntarily, anonymously, and generously donate (without compensation) either whole blood or separated components that are then processed and distributed by professionals, prior to being allocated to recipients in need. Being part of modern medicine,
Olivier Garraud+3 more
openaire +5 more sources