Results 61 to 70 of about 92,598 (347)

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

Advanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H. Kang   +4 more
wiley   +1 more source

Large‐Scale Production of Transfusion‐Ready Red Blood Cells From Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
A scalable, dynamic culture system is developed to produce red blood cells from induced pluripotent stem cells. It achieves high yields with up to 70% enucleation, not previously shown in dynamic systems, overcoming key limitations and enabling large‐scale production.
Eszter Varga, Eelke Brandsma, Brenda E. Juarez‐Garza, Renuka P. E. Ramlal, Julien J. Karrich, Adrien Laurent, Athina Chavli, Ruthmila Paskel, Kerly Fu, Richard A. Flavell, Marieke von Lindern, Derk Amsen, Marieke E. Klijn, Emile van den Akker   +13 more
wiley   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

Advanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu, Kaiqiang Li, Huasong Liu, Aibo Xu, Zhewei Zhang, Yimin Yang, Xiaobo Lai, Ke Hao, Kui Fang, Zeyu Lai, Xiping Ou, Yuqun Cai, Zhen Wang, Keda Lu, Wanli Jiang   +14 more
wiley   +1 more source

Rational Clinical Use of Blood and Blood products – A summary

Journal of Pathology of Nepal, 2017
Blood transfusion is an essential therapeutic intervention. The main role of the blood centre is to provide safe and timely blood and blood component(s) to the patients that will improve the physiological status of the patient.
D Ghartimagar
doaj   +1 more source

Whole blood as an alternative for component transfusion? [PDF]

ISBT Science Series, 2013
Blood services commonly separate whole blood (WB) into its components of red cells, platelets and plasma. This enables storage of the components under conditions that optimise their quality for as long as possible, and enables transfusion of only the required components to each recipient.
openaire   +2 more sources

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Rotational thormboelastolmetry guided transfusion practice in living donor liver transplantation, A retrospective comparative study

Egyptian Journal of Anaesthesia, 2018
Introduction: Living donor liver transplantation (LDLT) is a complex surgery with high risk for massive bleeding and blood component transfusion. This retrospective study investigated the effect of adopting ROTEM based transfusion algorithm on blood ...
Al-Refaey Kandeel, Usama Abdalla, Mohamed Abouelella, Mohammed Elmorshedi, Waleed Elsarraf, Mohammed Abdelwahab, Amr Yassen   +6 more
doaj  

Systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer [PDF]

, 2012
UCAN Cancer Charity (www.ucanhelp.org.uk) and MacMillan Cancer Charity (www.macmillan.org.uk) helped design and conduct the study.Peer ...
Canfield, Steven E., Dahm, Philipp, Griffiths, T. R. Leyshon, Hilvano-Cabungcal, Ana M., Imamura, Mari, Lam, Thomas B. L., Lapitan, Marie C., Ljungberg, Börje, MacLennan, Graeme, MacLennan, Sara J., MacLennan, Steven, McClinton, Sam, N'Dow, James, Omar, Muhammad Imran, Royle, Pam, Stewart, Fiona, UCAN Systematic Review Reference Group   +16 more
core   +1 more source

Multifunctional NIR‐Triggered Nanozyme‐Based Microneedles for Synergistic Eradication of MRSA and Enhanced Wound Healing

Advanced Science, EarlyView.
The novel microneedle patches (MN@CTB) are fabricated by integrating CTB nanozymes into HAMA and PVA solution based on a photo‐crosslinking reaction. The MN@CTB microneedle patches present an excellent photothermal effect and NIR‐stimulated release of NO, which is advantageous for the elimination of MRS.
Wei Qian, Ruixi Li, Xiyan Zheng, Yingliang Li, Haiwei Xiong, Ye Zhang, Dengliang Lei, Qingfeng Shi, Yufeng Xie, Yiting Zhou, Bailong Tao, Kuai Yu, Aiping Le, Boxuan Zhou   +13 more
wiley   +1 more source

Evaluation of blood requisition and utilization practices at a tertiary care hospital blood bank in Islamabad, Pakistan

Global Journal of Transfusion Medicine, 2017
Introduction: The significance of appropriate completion of blood request forms (BRFs) is frequently underrated by the clinicians which results in wastage and increased risk of inappropriate therapy. The judicious use of blood components can be assessed
Usman Waheed, Muneeba Azmat, Akhlaaq Wazeer, Sadia Sultan, Syed Muhammad Irfan, Hasan Abbas Zaheer   +5 more
doaj   +1 more source