Results 61 to 70 of about 512,121 (364)

Deep Placental Vessel Segmentation for Fetoscopic Mosaicking [PDF]

open access: yes, 2020
During fetoscopic laser photocoagulation, a treatment for twin-to-twin transfusion syndrome (TTTS), the clinician first identifies abnormal placental vascular connections and laser ablates them to regulate blood flow in both fetuses. The procedure is challenging due to the mobility of the environment, poor visibility in amniotic fluid, occasional ...
arxiv   +1 more source

An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment

open access: yesAdvanced Science, EarlyView.
Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su   +12 more
wiley   +1 more source

Effect of donor, component and recipient characteristics on hemoglobin increments following red blood cell transfusion.

open access: yesBlood, 2019
Significant research has focused individually on blood donors, product preparation and storage, and optimal transfusion practice. To better understand the interplay between these factors on measures of red blood cell (RBC) transfusion efficacy, we ...
Nareg H. Roubinian   +10 more
semanticscholar   +1 more source

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

open access: yesAdvanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang   +4 more
wiley   +1 more source

Whole blood as an alternative for component transfusion? [PDF]

open access: yesISBT Science Series, 2013
Blood services commonly separate whole blood (WB) into its components of red cells, platelets and plasma. This enables storage of the components under conditions that optimise their quality for as long as possible, and enables transfusion of only the required components to each recipient.
openaire   +2 more sources

Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling

open access: yesAdvanced Science, EarlyView.
This research presents a novel strategy employing the VGM cocktail, which combines HES7 overexpression with HDAC inhibitor and GABA, to enhance platelet production from hematopoietic stem and progenitor cells by promoting megakaryocyte progenitor (MkP) generation.
Huicong Liu   +6 more
wiley   +1 more source

Rational Clinical Use of Blood and Blood products – A summary

open access: yesJournal of Pathology of Nepal, 2017
Blood transfusion is an essential therapeutic intervention. The main role of the blood centre is to provide safe and timely blood and blood component(s) to the patients that will improve the physiological status of the patient.
D Ghartimagar
doaj   +1 more source

A linked donor-recipient study to evaluate parvovirus B19 transmission by blood component transfusion.

open access: yesBlood, 2009
Parvovirus B19V infection can be a serious infection for hematology patients with underlying hemolysis or compromised erythropoiesis syndromes. Although case reports of B19V transmission by blood component transfusion (as contrasted to manufactured ...
S. Kleinman   +8 more
semanticscholar   +1 more source

Colorectal Cancer Cells–Derived Exosomal PIK3CA Mutation DNA Promotes Tumor Metastasis by Activating Fibroblast and Affecting Tumor Metastatic Microenvironment

open access: yesAdvanced Science, EarlyView.
PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang   +6 more
wiley   +1 more source

Rotational thormboelastolmetry guided transfusion practice in living donor liver transplantation, A retrospective comparative study

open access: yesEgyptian Journal of Anaesthesia, 2018
Introduction: Living donor liver transplantation (LDLT) is a complex surgery with high risk for massive bleeding and blood component transfusion. This retrospective study investigated the effect of adopting ROTEM based transfusion algorithm on blood ...
Al-Refaey Kandeel   +6 more
doaj  

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