Results 71 to 80 of about 5,258,545 (311)

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

Advanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei, Changning Xue, Mengna Li, Jianxia Wei, Lemei Zheng, Shipeng Chen, Yijie Wang, Yumei Duan, Yanwei Luo, Wei Xiong, Ming Zhou   +10 more
wiley   +1 more source

Blood components requirement in Brazilian dengue outbreaks: A retrospective analysis between 2008 to 2019

Hematology, Transfusion and Cell Therapy
Introduction: Dengue is the most fatal virus disease spread by mosquito bites and Aedes aegypti is the main transmitting agent. It is an endemic disease in the tropical and subtropical regions, currently affecting more than 100 countries.
Deivide de Sousa Oliveira, Daniel Girão Britto, Gabriella Fidelis de Sá, Ana Carolina Nogueira Rocha Lima, João Victor Araújo Silva, Antonio Vinícius Barros de Araújo, Rejane Cavalcante Rebelo, Larissa Ciarlini Varandas Sales, Marcus Fábio Tavares de Abreu, Ednardo Ramos de Meneses   +9 more
doaj   +1 more source

The proposal to discontinue blood testing at the Munster Centre of the Irish Blood Transfusion Service Board (BTSB) - assessment by a representative regional group

, 1998
The role of the Irish Blood Transfusion Service is crucial to the operation of our health care system. In its 1965 Establishment Order, the key functions of the BTSB are described, inter alia, as follows (a) to take over the property {including chosen ...
Irish Blood Transfusion Service (IBTS)
core  

Evaluation of the Learnbloodtransfusion education programme: Module 1 Safe Transfusion Practice [PDF]

, 2011
This report is an evaluation of theLearnbloodtransfusion (LBT) module 1 Safe Transfusion Practice. It relates findings from a survey and in-depth interviews carried out with module participants.
Smith, Annetta, Doi, Larry, Atherton, Iain, Jepson, Ruth, Pirie, Elizabeth, Gray, Alexandra   +5 more
core  

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Utilización de la sangre y sus componentes celulares Use of blood and its cellular components

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2000
La terapia transfusional es una ciencia en constante renovación. En la actualidad las ventajas de la transfusión de componentes individuales han limitado el empleo de sangre total. Los parámetros clínicos y no la cifra de hemoglobina son determinantes al
Lázaro Cortina Rosales, María del Rosario López De Roux   +1 more
doaj  

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

OPERATIONAL INDICATORS OF BLOOD COMPONENT INVENTORY MANAGEMENT AT THE MANACAPURU BLOOD CENTER, AMAZONAS, BRAZIL

Hematology, Transfusion and Cell Therapy
Introduction: Maintaining an adequate blood component inventory requires balancing donor recruitment with transfusion demand. In the Brazilian Amazon, vast distances, reliance on river transportation, and seasonal hydrological variations pose additional ...
Juliane Kátia Moreira dos Santos CERINO, Emely Karen Dos Santos GANOZA, Janderson Barbosa de SOUZA, Paulo Mendes GUERREIRO, Nadielle Castro PEREIRA, Erick Frota Gomes FIGUEIREDO   +5 more
doaj   +1 more source

Blood component therapy: Which, when and how much

Journal of Anaesthesiology Clinical Pharmacology, 2011
Blood transfusion refers to the perioperative administration of blood and blood components. Adherence to proper indications for blood component therapy is essential because of its potential adverse effects and costs of transfusion.
Rajesh Chand Arya, G S Wander, Pankaj Gupta   +2 more
doaj   +1 more source