Results 221 to 230 of about 2,301,317 (358)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Analysis of Blood Components and Target Prediction for the Combined Use of <i>Dendrobium officinale</i> Compound and Western Medicine in Antihypertensive Therapy Based on Network Pharmacology and Molecular Docking. [PDF]

Drug Des Devel Ther
Wu R, Wang J, Zhou H, Xue X, Tong C, Zhao L, Wu Y, Mei X, Guo Z, Xi C.   +9 more
europepmc   +1 more source

A comprehensive protocol to evaluate the use of blood and its components in Latin America and the Caribbean

, 2015
Ana Emilia del Pozo, María Dolores Pérez-Rosales, Cesar de Almeida‐Neto, Mirta Remesar, Armando Cortés, Raquel Baumgratz Delgado, Alfredo Mendrone, Éster Cerdeira Sabino   +7 more
openalex   +1 more source

A Cross-sectional Study to Analyze Blood and Blood Component Transfusion Practice at Tertiary Care Hospital of Ethiopia

, 2021
Mahteme Bekele Muleta, Etsehiwot Haileselassie, Hana Abebe Gebreselassie, Tsega Terefe, Eden Berhanu, Adugna Lissanewerk Mekonnen, Woineshet Alaye, Gizachew Taddesse Akalu, Engida Abebe Gelan, Delayehu Bekele   +9 more
openalex   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The 'rejuvenating factor' TIMP-2 is detectable in human blood components for transfusion. [PDF]

Vox Sang, 2021
Hoefer J, Dal-Pont C, Jochberger S, Fantin R, Schennach H.   +4 more
europepmc   +1 more source

UTILITY OF BLOOD COMPONENTS IN PEDIATRIC PATIENTS – AN AUDIT

BLDE University
openalex   +1 more source

Relationship of Plasma Free Fatty Acids to Other Blood Components in Ruminants under Various Physiological Conditions

, 1966
H.D. Radloff, L.H. Schultz, W. G. Hoekstra   +2 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source