Results 131 to 140 of about 1,086,974 (316)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Evaluation of blood culture media supplemented with sucrose or with cysteine [PDF]

, 1975
John A. Washington, M M Hall, E Warren
openalex   +1 more source

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source

Hemoglobin biosynthesis in individual bursts in culture: studies of human umbilical cord blood [PDF]

, 1979
K Kidoguchi, Makio Ogawa, JD Karam, JS McNeil, MS Fitch   +4 more
openalex   +3 more sources

Bacteremia After Genitourinary Tract Manipulation: Bacteriological Aspects and Evaluation of Various Blood Culture Systems [PDF]

, 1972
Nadine M. Sullivan, Vera L. Sutter, W. T. Carter, Howard R. Attebery, S M Finegold   +4 more
openalex   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

The condition of test cultures especially as regards titration favourable to clear serum reactions by the dried blood method

, 1898
W. Ian H. Johnston, D. D. McTaggart
openalex   +2 more sources

Evidence for differentiation of human leukemic blood cells in diffusion chamber culture [PDF]

, 1977
D. Hoelzer, E. Kurrle, H. Schmücker, EB Harriss   +3 more
openalex   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Studies on the Effect of Adrenalin, Cortisone and ACTH on the White Blood Cell especially on the Eosinophilic Leukocyte by the Tissue Culture of the Bone Marrow-mainly on the mechanism of eosinopenia

, 1956
Shinrô Yamamoto
openalex   +2 more sources