Results 171 to 180 of about 2,359,639 (315)

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

Re‐thinking Strategies for a Pharmaceutical Approach to Pain‐related to Connective Tissue Related Raynaud's Phenomenon in the United States

open access: yesArthritis Care &Research, Accepted Article.
Introduction There are no Food and Drug Administration (FDA) approved therapies for Raynaud's phenomenon (RP) treatment in the United States (U.S.). Clinical trials have been challenged by study design. Important advances in RP patient reported outcome measures and mechanistic quantification allows RP‐related pain characterization.
Tracy M Frech   +4 more
wiley   +1 more source

Association Between Discordance of Disease Activity Indices and Quantitative Sensory Testing Measures of Nociplastic Pain in Patients With Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective This study investigates the association between discordance in commonly collected clinical indicators of rheumatoid arthritis (RA) disease activity and abnormalities in quantitative sensory testing (QST) observed in individuals with nociplastic pain.
Clarice P. Lin   +10 more
wiley   +1 more source

Using secure artificial intelligence agents integrated within the electronic medical record for the evaluation of blood culture appropriateness—Northern California, 2025 [PDF]

open access: hybrid
Guillermo Rodriguez-Nava   +15 more
openalex   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

An International, Prospective, Multicenter Evaluation of the Combination of AdvanDx Staphylococcus Quick FISH BC with mecA Xpress FISH for Detection of Methicillin-Resistant Staphylococcus aureus Isolates from Positive Blood Cultures [PDF]

open access: bronze, 2014
Hossein Salimnia   +16 more
openalex   +1 more source

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