ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
Introduction There are no Food and Drug Administration (FDA) approved therapies for Raynaud's phenomenon (RP) treatment in the United States (U.S.). Clinical trials have been challenged by study design. Important advances in RP patient reported outcome measures and mechanistic quantification allows RP‐related pain characterization.
Tracy M Frech +4 more
wiley +1 more source
What proportion of Salmonella Typhi cases are detected by blood culture? A systematic literature review [PDF]
Vittal Mogasale +3 more
openalex +1 more source
Objective This study investigates the association between discordance in commonly collected clinical indicators of rheumatoid arthritis (RA) disease activity and abnormalities in quantitative sensory testing (QST) observed in individuals with nociplastic pain.
Clarice P. Lin +10 more
wiley +1 more source
Using secure artificial intelligence agents integrated within the electronic medical record for the evaluation of blood culture appropriateness—Northern California, 2025 [PDF]
Guillermo Rodriguez-Nava +15 more
openalex +1 more source
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source
Model to evaluate the impact of hospital-based interventions targeting false-positive blood cultures on economic and clinical outcomes [PDF]
Benjamin P. Geisler +3 more
openalex +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
An International, Prospective, Multicenter Evaluation of the Combination of AdvanDx Staphylococcus Quick FISH BC with mecA Xpress FISH for Detection of Methicillin-Resistant Staphylococcus aureus Isolates from Positive Blood Cultures [PDF]
Hossein Salimnia +16 more
openalex +1 more source

