Results 231 to 240 of about 1,086,974 (316)

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

Advanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue, Tetsushi Taguchi, Taka‐Aki Asoh, Akihiro Nishiguchi   +3 more
wiley   +1 more source

Reducing laboratory delays in blood culture pathogen identification: a quality improvement project. [PDF]

BMJ Open Qual
Halstead FD, Pinjuh G, Antonacci G, Proudlove N.   +3 more
europepmc   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Performance of the LIAISON PLEX yeast blood culture assay for identifying 16 invasive fungal pathogens in blood cultures. [PDF]

J Clin Microbiol
Emery CL, Dhiman N, Chow S-K, Peterson G, Granato P, Bernier B, Farhang J.   +6 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Analysis of clinical characteristics of elderly patients with blood culture-positive bacterial liver abscess. [PDF]

Front Med (Lausanne)
Zhang HF, Chen JW, Li SS, Wu SW, Li S, Liu CY, Cai C, Lu MQ.   +7 more
europepmc   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source

Less haste, more speed: Does delayed blood culture transport time lead to adverse incubation times or yield?

J Infect
Deas G, Hamilton F, Williams P.
europepmc   +1 more source

Blood culture time to positivity in pediatric patients with bloodstream infection in rural Gambia. [PDF]

IJID Reg
Osei I, Wutor BM, Kuyateh A, Barjo O, Sarwar G, Omotosho M, Adefila WO, Olawale YA, Lamin KM, Hossain I, Lobga BG, Wally M, Cham M, Molfa M, Salaudeen R, Mackenzie GA.   +15 more
europepmc   +1 more source