Results 111 to 120 of about 79,579 (301)

Fear of Disease Progression in Patients with Type 2 Diabetes Construction and Validation of a Nomogram Prediction Model

International Journal of General Medicine
Xiaoxiao Liu,1,2 Junjun Wang,3 Haili Dong,2 Yanmin Zhao,4 Li Liu1 1Medical Insurance Department, Binzhou Medical University Hospital, Binzhou, Shandong, 256600, People’s Republic of China; 2College of Nursing, Binzhou Medical University, Binzhou ...
Liu X, Wang J, Dong H, Zhao Y, Liu L
doaj  

Factors associated with blood donation among college and university students in Wuhan, China: structural equation model

BMC Public Health
Background College and university students were an important population group of blood donors, especially in the current situation of tight blood supply.
Mengdi Ma, Ru Yang, Jun Gu, Songqing Ke, Xiaoan Du, Jie Zheng   +5 more
doaj   +1 more source

Predicting blood donation intentions and behavior among Australian blood donors: Testing an extended theory of planned behavior model

, 2009
BACKGROUND: Donor retention poses a significant problem to blood collection agencies around the world. Previous research using an augmented theory of planned behavior (TPB) approach has demonstrated that attitude, subjective norm, self-efficacy, moral ...
White, K., Terry, Deborah. J., K. Hyde, Melissa, White, Katherine M, White, Katherine. M., Katherine M. White, Hyde, M., Barbara M. Masser, J. Terry, Deborah, Terry, Deborah, Robinson, Natalie G, Terry, Deborah J., Masser, Barbara M., Terry, Deborah J, White, Katherine M., Natalie G. Robinson, G. Robinson, Natalie, Hyde, Melissa K, Masser, Barbara M, Robinson, N., Hyde, Melissa K., M. Masser, Barbara, Masser, B., Deborah J. Terry, Melissa K. Hyde, M. White, Katherine, Robinson, Natalie. G., Robinson, Natalie G.   +27 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Impact of donor transaminases on liver transplant utilisation and unnecessary organ discard: national registry cohort study

Frontiers in Transplantation
BackgroundDonor liver transaminases (ALT and AST) have been used to decline livers for transplant, despite evidence that they do not influence transplant outcomes.
Joseph J. Dobbins, Samuel J. Tingle, Samuel J. Tingle, Jennifer Mehew, Emily R. Thompson, Emily R. Thompson, Georgios Kourounis, Georgios Kourounis, Stuart McPherson, Steve A. White, Steve A. White, Colin H. Wilson, Colin H. Wilson   +12 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Motivating Altruism: A Field Study [PDF]

This paper analyzes the effects of a legislative provision that grants a one-day paid leave of absence to blood donors who are employees in Italy. The analysis is based on a unique dataset with the complete donation histories of the blood donors in an ...
Lacetera, Nicola, Macis, Mario
core  

Assessing blood donation applicant characteristics to optimize the promotion of apheresis

, 2020
For effectively using blood products from a limited donor population, the promotion of apheresis donation should be emphasized more often. This study assessed the demographic data of apheresis applicants using blood donor data from the Japanese Red Cross
KAWAHARA, Kazuo, KUMAZAWA, Daisuke, SUGAWA, Makiko   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source