Results 91 to 100 of about 79,579 (301)

Analysis of blood donor pre-donation deferral in Zhengzhou

open access: yes, 2022
Objective To identify low-risk donor population and optimize blood screening, recruitment and consultation strategies via retrospectively analyzing the unqualified results of Hb, ALT, HBsAg, TP before whole blood donation from 2015 to 2018.
Min LIU, Tianning SI, Xinli JIN, Tao WEN
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Ethical and Medical Considerations for a Blood Donation Programme in a Refugee Population

open access: yes, 1988
The screening of donors, laboratory procedures, and nutritional supplementation used in a blood donation program at a camp for Khmer refugees along the Thai-Kampuchean border are described.
Dexter, Roy   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

UMP recognised as most active blood donation organiser [PDF]

open access: yes, 2022
KUANTAN, 14 June 2022 - Universiti Malaysia Pahang (UMP) received the 2021 Most Active Organiser award in conjunction with the recent Pahang statewide World Blood Donor Day ...
Nor Salwana, Mohammad Idris
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Knowledge, attitude, and practice regarding voluntary blood donation among adult residents of Harar town, Eastern Ethiopia: a community-based study

open access: yes, 2017
Kedir Urgesa,1 Nejat Hassen,2 Ayichew Seyoum1 1Department of Medical Laboratory Sciences, 2Department of Public Health, Haramaya University, Harar, Ethiopia Background: The availability of safe blood and blood products is a critical factor in ...
Hassen N, Seyoum A, Urgesa K
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Blood Donation and Associated Factors Among Employees Working at Negele Arsi General Hospital and Medical College, Southeast Ethiopia: A Cross-sectional Study

open access: yes, 2021
Ashebir Nigussie Yirgu,1 Kassim Hussien Mohammed,2 Sisay Degno Diriba,3 Abdella Kumbi Babso,4 Abdella Amano Abdo5 1Negele Arsi General Hospital and Medical College, Department of Anesthesia, Negele Arsi, Ethiopia; 2Department of Sociology, Negele Arsi ...
Abdo AA   +4 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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