Results 71 to 80 of about 231,288 (293)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Double Red Blood Cell Donation Eligibility and Interest [PDF]

, 2010
Introduction: The process of double RBC donation by apheresis (DRBC), which facilitates the donation of two units of red blood cells (RBC) in a single donation session, was estimated to account for approximately 4% of blood donations in 2005, and is ...
Anderson, Laura, Bessoff, Kovi, Carney, Jan, Chapman, Brandon, Dembeck, Carol, Dunn, Angela, Frenette, Christine, Fung, Mark K., Larochelle, Michael, Scripps, Tessa, Wood, Jessica   +10 more
core   +1 more source

International forum. an investigation of iron status in blood donors [PDF]

, 2017
No abstract ...
Anderson, Nicky, Antoniewicz Papis, Jolanta, Argyrou, Isabella, Bokhorst, Arlinke, Borg Aquilina, Denise, Burta, Olivia L, Castrén, Johanna, Compernolle, Veerle, Danic, Bruno, Daugavvanaga, Anita, De Kort, Wim, Djoudi, Rachid, Faber, Jean Claude, Folléa, Gilles, Karakatsiani, Georgia, Khanirzajeva, Gulara, Liumbruno, Giancarlo M, Magnussen, Karin, Mali, Polonca, Masharova, Natalia, Mueller, Markus M, Muon, Mario, Norda, Rut, Pogłód, Ryszard, Politis, Constantina, Rosochová, Jana, Schennach, Harald, Schneider, Karin, Vaglio, Stefania, Van Den Burg, Peter, Vandewalle, Giovani, Vesga, Miguel A, Vilutyte, Edita, Vuk, Tomislav, Woimant, Geneviève, Řeháček, Vít   +35 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The role of vitamin D in the prevention and treatment of acute respiratory infections in pediatric populations: a systematic review and meta-analysis of randomized controlled trials

BMC Pediatrics
Background Acute respiratory infections (ARIs) remain a leading cause of morbidity and mortality in pediatric populations worldwide. Vitamin D has immunomodulatory functions that may influence susceptibility and outcomes of respiratory infections, yet ...
Lan Wang, Yabin Yu, Kaifang Liu, Xin Yu, Ying Li   +4 more
doaj   +1 more source

From byproduct to biotherapeutic: Comparative study of buffy coats and leukoreduction system chambers for NK cell-based immunotherapies

iScience
Summary: Natural killer (NK) cell immunotherapies require reliable access to large numbers of functionally consistent cells, yet obtaining sufficient material remains challenging.
Maximiliane Tietze, Maria Schuldt, Martina Wohsmann, Kristina Hölig, Helmut Hanenberg, Torsten Tonn, Jiri Eitler, Joel G. Rurik, Stephan R. Künzel   +8 more
doaj   +1 more source

Should 16-Year-Olds Be Allowed to Donate Blood? A Vermont Perspective [PDF]

, 2012
Introduction: Supplying adequate blood for transfusions is an ongoing challenge for blood collection agencies. One potential source of increased Whole Blood (WB) supply is among 16-17 year-olds, whose donation rates are still quite low.
Carney, Jan, Crowl, Gabriel, Daud, Anees, Dembeck, Carol, Franz, Vanessa, Frenette, Chris, Fung, Mark K, Phillips, Nicholas, Pinsky, Maia, Pons, Jennifer, Zingiryan, Areg   +10 more
core   +1 more source