Results 61 to 70 of about 79,579 (301)

Transcriptomic profiling during normothermic machine perfusion of human kidneys reveals a pro-inflammatory cellular landscape and gene expression signature associated with severe ischemia-reperfusion injury and delayed graft function

Frontiers in Immunology
BackgroundAssessment and treatment of severe ischemia-reperfusion-injury (IRI) remains an unmet challenge in kidney transplantation. Normothermic machine perfusion (NMP) recapitulates IRI ex situ, but there is limited understanding of the transcriptional
Harry V. M. Spiers, Harry V. M. Spiers, Harry V. M. Spiers, Sarah A. Hosgood, Sarah A. Hosgood, Sarah A. Hosgood, Miguel Larraz, Miguel Larraz, Lukas J. K. Stadler, Lukas J. K. Stadler, Ying Zhai, Ying Zhai, Haeun Moon, Haeun Moon, Serena MacMillan, Serena MacMillan, Anna Paterson, Anna Paterson, Michael L. Nicholson, Michael L. Nicholson, Michael L. Nicholson, Irina Mohorianu, Irina Mohorianu, Irina Mohorianu, Vasilis Kosmoliaptsis, Vasilis Kosmoliaptsis, Vasilis Kosmoliaptsis   +26 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Complete tracheal transection at the thoracic inlet: successful reconstruction with intraoperative Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) support – case report

International Journal of Emergency Medicine
Background Tracheobronchial injuries from blunt chest trauma carry high mortality, with complete thoracic inlet tracheal transection being previously undocumented.
Huade Luo, Lingling Jiang, Dongying Wang
doaj   +1 more source

Donor Blood Tests do Not Predict Pancreas Graft Survival After Simultaneous Pancreas Kidney Transplantation; a National Cohort Study

Transplant International
Simultaneous pancreas-kidney (SPK) transplantation improves quality of life and limits progression of diabetic complications. There is reluctance to accept pancreata from donors with abnormal blood tests, due to concern of inferior outcomes.
Ning Xuan Ho, Samuel J. Tingle, Samuel J. Tingle, Abdullah K. Malik, Abdullah K. Malik, Emily R. Thompson, Emily R. Thompson, Georgios Kourounis, Georgios Kourounis, Aimen Amer, Aimen Amer, Sanjay Pandanaboyana, Sanjay Pandanaboyana, Colin Wilson, Colin Wilson, Steve White, Steve White   +16 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Prevalence of Hepatitis B in Canadian First-Time Blood Donors: Association with Social Determinants of Health

Viruses
Hepatitis B is transmitted sexually, by blood contact, and vertically from mother to child. Chronic hepatitis B is often seen in immigrants from higher-prevalence countries and their Canadian-born children.
Sheila F. O’Brien, Behrouz Ehsani-Moghaddam, Mindy Goldman, Steven J. Drews   +3 more
doaj   +1 more source

Awareness and practice of cord blood donation by pregnant women in Lagos Nigeria: Practice implication for future cord blood transplantation in Nigeria

, 2021
Background: Poor awareness remains a substantial limitation to harnessing the benefits of umbilical cord blood (UCB) in sub-Saharan Africa. The aim of this study was to determine the level of awareness and factors influencing intention to donate cord ...
Oyedeji, O.A., Olorunfemi, G., Okunade, K.S., John-Olabode, S.O., Ajie, I.O.   +4 more
core   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Empirically derived dietary patterns and constipation among a middle-aged population from China, 2016–2018

Nutrition Journal, 2019
Background The association of dietary patterns with constipation is not well established, particularly in Chinese population. Therefore, the present study aimed to determine the relationship between dietary patterns and the risk of constipation in a ...
Li Li, Ai-Ping Huang, Li-Qin Wang, Xiao-Long Yu   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source