Results 1 to 10 of about 3,039,068 (260)

Neither COVID-19, nor cryopreservation, prevented allogeneic product infusion: A report from the National Marrow Donor Program

Frontiers in Immunology, 2022
BackgroundThe Coronavirus Disease 2019 (COVID-19) pandemic in early 2020 has resulted in an unprecedented level of uncertainty and challenge for the stem cell donor registries.
Nosha Farhadfar, Jeni Newman, Jennifer Novakovich, Jacklyn Barten, Eric T. Ndifon, Jason Oakes, Meghann Cody, Huy P. Pham, Jeffery J. Auletta, Jeffery J. Auletta, John P. Miller, Steven M. Devine, Heather E. Stefanski   +12 more
doaj   +1 more source

A snapshot of ABO, RH, and JK blood group systems in modern Ireland

Health Science Reports, 2021
Objectives This study aimed to capture a snapshot of the Irish population to determine if there had been any changes in the ABO and RH blood group system (BGS) distribution from previous Irish studies and to establish an Irish JK BGS frequency, providing
Anne Browne, Anthony Kinsella, Moira Keogh, Kieran Morris, Stephen Field   +4 more
doaj   +1 more source

Small volume bone marrow aspirates with high progenitor cell concentrations maximize cell therapy dose manufacture and substantially reduce donor hemoglobin loss

BMC Medicine, 2023
Background Bone marrow (BM) transplantation is a life-saving therapy for hematological diseases, and the BM harbors also highly useful (progenitor) cell types for novel cell therapies manufacture.
Jeremy Epah, Gabriele Spohn, Kathrin Preiß, Markus M. Müller, Johanna Dörr, Rainer Bauer, Shabnam Daqiq-Mirdad, Joachim Schwäble, Stefanie N. Bernas, Alexander H. Schmidt, Erhard Seifried, Richard Schäfer   +11 more
doaj   +1 more source

Worldwide survey on key indicators for public cord blood banking technologies: By the World Marrow Donor Association Cord Blood Working Group

Stem Cells Translational Medicine, 2021
The Cord Blood Working Group of the World Marrow Donor Association created a survey for cord blood banks (CBBs) aimed to identify and understand the main technical procedures currently used by public CBBs worldwide regarding cord blood units (CBUs ...
Monique Jöris, Katie Paulson, Lesa Foley, Merry Duffy, Sergio Querol, Susana Gomez, Etienne Baudoux   +6 more
doaj   +1 more source

Ferritin-guided iron supplementation in whole blood donors: optimal dosage, donor response, return and efficacy (FORTE)—a randomised controlled trial protocol

BMJ Open, 2022
Background Frequent whole blood donors have an increased risk of developing iron deficiency. Iron deficiency can have detrimental health effects when left untreated.
Katja van den Hurk, Maike G Sweegers, Dorine W Swinkels, Jan Karregat, Franke A Quee, Henriëtte H Weekamp, Vĕra M J Novotny, Hans L Zaaijer   +7 more
doaj   +1 more source

From Unit to Dose: A Machine Learning Approach for Precise Prediction of Hemoglobin and Iron Content in Individual Packed Red Blood Cell Units

Advanced Science, 2022
Transfusion of packed red blood cells (pRBCs) saves lives, but iron overload limits survival of chronically transfused patients. Quality control methods, which involve entering pRBC units and removing them from the blood supply, reveal that hemoglobin ...
Jeremy Epah, Ilay Gülec, Stefan Winter, Johanna Dörr, Christof Geisen, Eva Haecker, Dietmar Link, Matthias Schwab, Erhard Seifried, Richard Schäfer   +9 more
doaj   +1 more source

Absence of the CXCR4 antagonist EPI-X4 from pharmaceutical human serum albumin preparations

Journal of Translational Medicine, 2021
Background Endogenous Peptide Inhibitor of CXCR4 (EPI-X4) is a natural antagonist of the CXC chemokine receptor 4 (CXCR4). EPI-X4 is a 16-mer peptide that is released from human serum albumin (HSA) by acidic aspartic proteases such as Cathepsin D and E ...
Andrea Gilg, Mirja Harms, Lia-Raluca Olari, Ann-Kathrin Urbanowitz, Halvard Bonig, Jan Münch   +5 more
doaj   +1 more source

AMBIGUITY OF LOCI DURING HLA-TYPING ON SSO TECHNOLOGY AND ATTEMPT TO RESOLVE THEM

Вестник трансплантологии и искусственных органов, 2010
Sequence specific oligonucleotides typing was used to identify human leukocyte antigen (HLA)-A, B, DRB1 alleles from 705 recruited volunteers with Volga Federal District for unrelated hematopoietic stem cell registry and 155 of their number at locus HLA ...
M. A. Loginova, I. V. Paramonov, N. P. Trofimova   +2 more
doaj   +1 more source

Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells

eLife, 2020
Acute Myeloid Leukemia (AML) is an aggressive hematological malignancy with abnormal progenitor self-renewal and defective white blood cell differentiation.
Ana Filipa Domingues, Rashmi Kulkarni, George Giotopoulos, Shikha Gupta, Laura Vinnenberg, Liliana Arede, Elena Foerner, Mitra Khalili, Rita Romano Adao, Ayona Johns, Shengjiang Tan, Keti Zeka, Brian J Huntly, Sudhakaran Prabakaran, Cristina Pina   +14 more
doaj   +1 more source

Pooled human bone marrow-derived mesenchymal stromal cells with defined trophic factors cargo promote dermal wound healing in diabetic rats by improved vascularization and dynamic recruitment of M2-like macrophages

Frontiers in Immunology, 2022
Human Mesenchymal Stromal Cells (hMSCs) are a promising source for cell-based therapies. Yet, transition to phase III and IV clinical trials is remarkably slow.
Hélène Willer, Hélène Willer, Gabriele Spohn, Kimberly Morgenroth, Corinna Thielemann, Susanne Elvers-Hornung, Peter Bugert, Bruno Delorme, Melanie Giesen, Thomas Schmitz-Rixen, Erhard Seifried, Christiane Pfarrer, Richard Schäfer, Richard Schäfer, Richard Schäfer, Karen Bieback, Karen Bieback, Karen Bieback   +17 more
doaj   +1 more source