Results 31 to 40 of about 5,409,262 (407)

Human mesenchymal stromal cells inhibit platelet activation and aggregation involving CD73-converted adenosine

Stem Cell Research & Therapy, 2018
Background Mesenchymal stromal cells (MSCs) are promising cell therapy candidates. Clinical application is considered safe. However, minor side effects have included thromboembolism and instant blood-mediated inflammatory reactions suggesting an effect ...
P. Netsch, S. Elvers-Hornung, S. Uhlig, H. Klüter, V. Huck, F. Kirschhöfer, G. Brenner-Weiß, K. Janetzko, H. Solz, P. Wuchter, P. Bugert, K. Bieback   +11 more
doaj   +1 more source

2014 European Conference on Donor Health and Management. [PDF]

, 2015
The first European Conference on Donor Health and Management was held in the Hague from 3th- 5th September 2014 and hosted by Sanquin, the Dutch national blood donation organization.
Di Angelantonio, E, Ramond, A
core   +1 more source

History and Future of Nucleic Acid Amplification Technology Blood Donor Testing

Transfusion Medicine and Hemotherapy, 2019
The introduction of blood donor screening by virus nucleic acid amplification technology (NAT) in the mid to late 1990s was driven by the so-called AIDS and hepatitis C virus (HCV) epidemic, with thousands of recipients of infected blood products and ...
W. Roth
semanticscholar   +1 more source

Large genome-wide association study identifies three novel risk variants for restless legs syndrome

Communications Biology, 2020
Didriksen, Nawaz, et al. identify three novel genetic risk variants for restless legs syndrome and confirm 19 out of 20 previously reported variants through a genome-wide association meta-analysis including nearly half a million individuals.
Maria Didriksen, Muhammad Sulaman Nawaz, Joseph Dowsett, Steven Bell, Christian Erikstrup, Ole B. Pedersen, Erik Sørensen, Poul J. Jennum, Kristoffer S. Burgdorf, Brendan Burchell, Adam S. Butterworth, Nicole Soranzo, David B. Rye, Lynn Marie Trotti, Prabhjyot Saini, Lilja Stefansdottir, Sigurdur H. Magnusson, Gudmar Thorleifsson, Thordur Sigmundsson, Albert P. Sigurdsson, Katja Van Den Hurk, Franke Quee, Michael W. T. Tanck, Willem H. Ouwehand, David J. Roberts, Eric J. Earley, Michael P. Busch, Alan E. Mast, Grier P. Page, John Danesh, Emanuele Di Angelantonio, Hreinn Stefansson, Henrik Ullum, Kari Stefansson   +33 more
doaj   +1 more source

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

Communications Biology, 2021
Bell et al. report 46 new loci associated with biomarkers of iron homeostasis, including ferritin levels, iron binding capacity, and iron saturation, in the Icelandic, Danish and UK populations.
Steven Bell, Andreas S. Rigas, Magnus K. Magnusson, Egil Ferkingstad, Elias Allara, Gyda Bjornsdottir, Anna Ramond, Erik Sørensen, Gisli H. Halldorsson, Dirk S. Paul, Kristoffer S. Burgdorf, Hannes P. Eggertsson, Joanna M. M. Howson, Lise W. Thørner, Snaedis Kristmundsdottir, William J. Astle, Christian Erikstrup, Jon K. Sigurdsson, Dragana Vuckovic, Khoa M. Dinh, Vinicius Tragante, Praveen Surendran, Ole B. Pedersen, Brynjar Vidarsson, Tao Jiang, Helene M. Paarup, Pall T. Onundarson, Parsa Akbari, Kaspar R. Nielsen, Sigrun H. Lund, Kristinn Juliusson, Magnus I. Magnusson, Michael L. Frigge, Asmundur Oddsson, Isleifur Olafsson, Stephen Kaptoge, Henrik Hjalgrim, Gudmundur Runarsson, Angela M. Wood, Ingileif Jonsdottir, Thomas F. Hansen, Olof Sigurdardottir, Hreinn Stefansson, David Rye, DBDS Genomic Consortium, James E. Peters, David Westergaard, Hilma Holm, Nicole Soranzo, Karina Banasik, Gudmar Thorleifsson, Willem H. Ouwehand, Unnur Thorsteinsdottir, David J. Roberts, Patrick Sulem, Adam S. Butterworth, Daniel F. Gudbjartsson, John Danesh, Søren Brunak, Emanuele Di Angelantonio, Henrik Ullum, Kari Stefansson   +61 more
doaj   +1 more source

Detection of HIV-1 infection in dried blood spots from a 12-year-old ABO bedside test card [PDF]

, 1998
Background and Objectives: We tested dried blood from an ABO bedside test card which had been stored at room temperature for 12 years, to prove that a patient with HIV-1 infection had been infected by blood transfusion. Materials and Methods: Immunoblots
Eberle, J., Emminger, Ch., Gürtler, L., Mayer, G., Strobel, Erwin   +4 more
core   +1 more source

Effectiveness of blood donor screening by HIV, HCV, HBV‐NAT assays, as well as HBsAg and anti‐HBc immunoassays in Germany (2008–2015)

Vox Sanguinis, 2019
In Germany, in addition to standard blood donor screening, further mandatory tests were introduced for HCV‐RNA, HIV‐1‐RNA and for anti‐HBc. Screening for HBV‐DNA is optional.
S. Fiedler, D. Oberle, M. Chudy, H. Scheiblauer, O. Henseler, J. Halbauer, M. Heiden, M. Funk   +7 more
semanticscholar   +1 more source

Whole-blood sorting, enrichment and in situ immunolabeling of cellular subsets using acoustic microstreaming [PDF]

, 2018
Analyzing undiluted whole human blood is a challenge due to its complex composition of hematopoietic cellular populations, nucleic acids, metabolites, and proteins. We present a novel multi-functional microfluidic acoustic streaming platform that enables
Garg, Neha, Lee, Abraham P, Liu, Robin, Liu, Vick, Nelson, Edward L, Westerhof, Trisha M   +5 more
core   +1 more source

Whole-genome sequencing identifies novel predictors for hematopoietic cell transplant outcomes for patients with myelodysplastic syndrome: a CIBMTR study

Journal of Hematology & Oncology, 2023
Recurrent mutations in TP53, RAS pathway and JAK2 genes were shown to be highly prognostic of allogeneic hematopoietic cell transplant (alloHCT) outcomes in myelodysplastic syndromes (MDS).
Tao Zhang, Paul Auer, Jing Dong, Corey Cutler, Amy E. Dezern, Shahinaz M. Gadalla, H. Joachim Deeg, Aziz Nazha, Karen-Sue Carlson, Stephen Spellman, Yung-Tsi Bolon, Wael Saber   +11 more
doaj   +1 more source

Providing health checks as incentives to retain blood donors — evidence from two field experiments [PDF]

, 2018
The collection of blood given by donors has proven to be a substantial societal and a managerial challenge. Consequently, blood donation services seek for incentive mechanisms to retain donors.
Clement, Michel, de Vries, Martha, Leipnitz, Sigrun, Mazar, Nina   +3 more
core   +1 more source