Results 71 to 80 of about 356,868 (313)

GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia. [PDF]

, 2019
We report graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) (a composite end point of survival without grade III-IV acute GVHD [aGVHD], systemic therapy-requiring chronic GVHD [cGVHD], or relapse) and cGVHD-free relapse-free survival ...
Abdel-Azim, Hisham, Ahmed, Ibrahim, Aljurf, Mahmoud, Alousi, Amin M., Arora, Mukta, Askar, Medhat, Auletta, Jeffery J., Bhatt, Vijaya, Bredeson, Christopher, Chhabra, Saurabh, Couriel, Daniel R., Diaz, Miguel Angel, Gadalla, Shahinaz, Gajewski, James, Gale, Robert Peter, Gergis, Usama, Hematti, Peiman, Hemmer, Michael T., Hildebrandt, Gerhard C., Holtan, Shernan G, Inamoto, Yoshihiro, Khandelwal, Pooja, Kitko, Carrie, MacMillan, Margaret L., Majhail, Navneet, Marks, David I., Mehta, Parinda, Mehta, Rohtesh S., Nishihori, Taiga, Olsson, Richard F., Pawarode, Attaphol, Pidala, Joseph, Prestidge, Tim, Qayed, Muna, Rangarajan, Hemalatha, Ringden, Olle, Saad, Ayman, Savani, Bipin N., Schultz, Kirk R., Seo, Sachiko, Shah, Ami, Shah, Niketa, Solh, Melhem, Spellman, Stephen R., Spitzer, Thomas, Szer, Jeffrey, Teshima, Takanori, Verdonck, Leo F, Wagner, John, Wang, Tao, Weisdorf, Daniel J., Williams, Kirsten M., Wirk, Baldeep, Yared, Jean A.   +53 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol

Frontiers in Oncology, 2013
Allogeneic Natural Killer (NK) cells are used for adoptive immunotherapy after stem cell transplantation. In order to overcome technical limitations in NK cell purification and activation, the following study investigates the impact of different ...
Ulrike eKoehl, Claudia eBrehm, Sabine eHuenecke, Stephan eKloess, Melanie eBremm, Stefanie Yvonne eZimmermann, Evelyn eUllrich, Jan eSoerensen, Andrea eQuaiser, Stephanie eErben, Claudia eWunram, Tanja eGardlowski, Eileen eAuth, Eileen eAuth, Torsten eTonn, Chritian eSeidl, Sandrine eMeyer-Monard, Martin eStern, Jakob ePassweg, Thomas eKlingebiel, Peter eBader, Dirk eSchwabe, Ruth eEsser   +22 more
doaj   +1 more source

Lymphoid/nonlymphoid compartmentalization of donor leukocyte chimerism in rat recipients of heart allografts, with or without adjunct bone marrow [PDF]

, 1998
Background. The role of leukocyte migration and chimerism in organ allograft acceptance has been obscured by the lack of information about the late localization of the donor cells. Methods.
Demetris, AJ, Murase, N, Starzl, TE, Terakura, M, Thomson, AW, Ye, Q   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A Conceptual Framework for Optimizing Blood Matching Strategies: Balancing Patient Complications Against Total Costs Incurred

Frontiers in Medicine, 2018
Alloimmunization is currently the most frequent adverse blood transfusion event. Whilst completely matched donor blood would nullify the alloimmunization risk, this is practically infeasible.
Joost H. J. van Sambeeck, Joost H. J. van Sambeeck, Puck D. de Wit, Jessie Luken, Barbera Veldhuisen, Barbera Veldhuisen, Katja van den Hurk, Anne van Dongen, Maria M. W. Koopman, Marian G. J. van Kraaij, Marian G. J. van Kraaij, Marian G. J. van Kraaij, C. Ellen van der Schoot, Henk Schonewille, Wim L. A. M. de Kort, Wim L. A. M. de Kort, Mart P. Janssen   +16 more
doaj   +1 more source

A novel, nondestructive, dried blood spot-based hematocrit prediction method using noncontact diffuse reflectance spectroscopy [PDF]

, 2016
Dried blood spot (DBS) sampling is recognized as a valuable alternative sampling strategy both in research and in clinical routine. Although many advantages are associated with DBS sampling, its more widespread use is hampered by several issues, of which
Aalders, Maurice CG, Capiau, Sara, Stove, Christophe, Wilk, Leah S   +3 more
core   +4 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Type 1 diabetes mellitus after cord blood transplantation from an unrelated donor with a disease‐sensitive haplotype [PDF]

, 2022
Kensuke Matsumoto, Taisuke Matsuyama, Ritsu Sumiyoshi, Takuji Matsuo, Tadashi Yamamoto, Ryosuke Shirasaki, Haruko Tashiro   +6 more
openalex   +1 more source

Liver transplantation across ABO blood groups [PDF]

, 1986
Six hundred seventy-one first, second, and third orthotopic liver allografts in 520 patients were reviewed to determine the effect of donor-recipient mismatches or incompatibility for the ABO blood group on graft survival. A significant advantage for ABO
Esquivel, CO, Gordon, RD, Iwatsuki, S, Starzl, TE, Todo, S, Tzakis, A   +5 more
core