Results 141 to 150 of about 11,049,702 (406)

Pulmonary consequences of experimentally induced stroke: differences between global and focal cerebral ischemia

Frontiers in Physiology
IntroductionCerebral ischemia leads to multiple organ dysfunctions, with the lungs among the most severely affected. Although adverse pulmonary consequences contribute significantly to reduced life expectancy after stroke, the impact of global or focal ...
Petra Somogyi, Petra Somogyi, Petra Somogyi, Ibolya Tóth, Bence Ballók, Zaid Hammad, Ramez A. Hussein, Fruzsina Kun-Szabó, József Tolnai, Judit Danis, Szilvia Kecskés, Szilvia Kecskés, Gergely H. Fodor, Eszter Farkas, Eszter Farkas, Ferenc Peták   +15 more
doaj   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Evidence from venous oxygen saturation measurements that the increase in forearm blood flow during body heating is confined to the skin

, 1956
I. C. Roddie, John T. Shepherd, R. F. Whelan   +2 more
openalex   +2 more sources

High-Spatial Resolution Laser Doppler Blood Flow Imaging [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Hayes-Gill, BR, He, D, Morgan, SP, Sun, S   +4 more
core  

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

The Effect of Hexamethonium upon Cerebral Blood Flow and Metabolism in Patients with Premalignant and Malignant Hypertension [PDF]

, 1955
Charles W. Crumpton, George G. Rowe, ROBERT C. CAPPS, JANET J. WHITMORE, Q. R. Murphy   +4 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Prominent role of platelets in the formation of circulating neutrophil-red cell heterocellular aggregates in sickle cell anemia

Haematologica, 2014
Venina M. Dominical, Leigh Samsel, James S. Nichols, Fernando F. Costa, J. Phillip McCoy, Nicola Conran, Gregory J. Kato   +6 more
doaj   +1 more source

The pathogenesis of microglia in traumatic brain injury

Chinese Journal of Contemporary Neurology and Neurosurgery
The mechanism of secondary injury after tramatic brain injury (TBI) is related to inflammation reation, oxidative stress, inflammasome, and so on, and microglia are closely related to it. Microglia, as macrophage in the nervous system, participate in the
HAN Jia-liang, ZHANG Guo-bin
doaj   +1 more source

The effect of noradrenaline infusions on the blood flow through the human forearm

, 1954
H. Barcroft, Peter Gaskell, John T. Shepherd, R. F. Whelan   +3 more
openalex   +2 more sources