Results 151 to 160 of about 11,240,256 (401)

Transcatheter aortic valve implantation improves carotid and vertebral arterial blood flow in patients with severe aortic stenosis: practical role of orthostatic stress test [PDF]

, 2017
Paweł Kleczyński, Paweł Petkow Dimitrow, Artur Dziewierz, Andrzej Surdacki, Dariusz Dudek   +4 more
openalex   +1 more source

Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease

Nature Reviews Neuroscience, 2017
Kassandra Kisler, Amy R. Nelson, Axel Montagne, B. Zlokovic   +3 more
semanticscholar   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Prominent role of platelets in the formation of circulating neutrophil-red cell heterocellular aggregates in sickle cell anemia

Haematologica, 2014
Venina M. Dominical, Leigh Samsel, James S. Nichols, Fernando F. Costa, J. Phillip McCoy, Nicola Conran, Gregory J. Kato   +6 more
doaj   +1 more source

Effects of photodynamic therapy on subfoveal blood flow in neovascular age-related macular degeneration patients [PDF]

, 2009
V. Vinh Moreau-Gaudry, Martial Geiser, J.P. Romanet, Ruxandra Hera, Julie Millet, Christophe Chiquet   +5 more
openalex   +1 more source

Capillary pericytes regulate cerebral blood flow in health and disease

Nature, 2014
C. Hall, C. Reynell, Bodil Gesslein, N. Hamilton, Anusha Mishra, B. Sutherland, F. O'Farrell, A. Buchan, M. Lauritzen, D. Attwell   +9 more
semanticscholar   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

The effects of short-term venous congestion on forearm venous volume and reactive hyperemia blood flow in human subjects. [PDF]

, 1978
Robert Zelis, Robert J. Capone, Edward Mansour, John M. Field   +3 more
openalex   +1 more source

Glial and neuronal control of brain blood flow

Nature, 2010
D. Attwell, A. Buchan, S. Charpak, M. Lauritzen, B. MacVicar, E. Newman   +5 more
semanticscholar   +1 more source