Results 41 to 50 of about 6,628,243 (289)
Chinese Journal of Contemporary Neurology and NeurosurgeryObjective To evaluate the efficacy and safety of spinal cord stimulation (SCS) in the treatment of high-risk diabetic foot. Methods From January 2023 to May 2024, 25 patients with high-risk diabetic foot who underwent SCS were admitted to Tianjin Huanhu ...
CHEN Xiao-chen +4 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Haematologica, 2016 Iron overload results in significant morbidity and mortality in β-thalassemic patients. Insufficient hepcidin is implicated in parenchymal iron overload in β-thalassemia and approaches to increase hepcidin have therapeutic potential.
Huiyong Chen +13 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
The role of large arteries in controlling blood flow to the hand during severe local cooling. [PDF]
, 1995 PhDCold vasodilatation describes the increase in blood flow that follows initial vaso constriction when an extremity is exposed to an environment colder than 12'C. It appears to be due mainly to cold paralysis of local resistance vessels.
Whelan, Laurence John
core +4 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Hypothalamic-pituitary dysfunction in severe traumatic brain injury long-term outcomes
Chinese Journal of Contemporary Neurology and NeurosurgeryThe incidence of hypothalamic-pituitary dysfunction in patients with severe traumatic brain injury (sTBI) reaches up to 40%. However, it is often masked by clinical manifestations similar to those of sTBI, leading to underdiagnosis and misdiagnosis ...
QIU Bing-hui +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Mediators of Inflammation, 2006 Background. The cytokine network remarkably influences homeostasis. There is not a complex analysis describing physiological values of soluble cytokines in healthy individuals. Methods.
Klabusay Martin +4 more
doaj +1 more source
Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry
Frontiers in Immunology, 2019 Canonical inflammasome activation is a tightly regulated process that has been implicated in a broad spectrum of inflammatory disorders. Inflammasome formation requires assembly of a cytosolic sensor protein with the adapter, ASC (apoptosis-associated ...
Silvia Lucena Lage +3 more
doaj +1 more source