Results 41 to 50 of about 3,014,726 (209)

Diagnosis of venous incompetence inerectile dysfunction [PDF]

, 1990
In 26 of 214 patients with erectile dysfunction and proved venous incompetence by cavernosography, an additional bidirectional Doppler ultrasound was performed also to demonstrate venous outflow disturbances. All except one leakage in the superficial and
Bähren, Wolfgang, Gall, Helmut, Holzki, G., Scherb, Wolfgang, Sparwaser, C. H., Stief, Christian Georg   +5 more
core   +1 more source

Hypothalamic-pituitary dysfunction in severe traumatic brain injury long-term outcomes

Chinese Journal of Contemporary Neurology and Neurosurgery
The incidence of hypothalamic-pituitary dysfunction in patients with severe traumatic brain injury (sTBI) reaches up to 40%. However, it is often masked by clinical manifestations similar to those of sTBI, leading to underdiagnosis and misdiagnosis ...
QIU Bing-hui, DU Jia-shu, ZHONG Qing-lei, ZHUO Jie, HE Shan   +4 more
doaj   +1 more source

Simultaneous analysis of cytokines and co-stimulatory molecules concentrations by ELISA technique andof probabilities of measurable concentrations of interleukins IL-2, IL-4, IL-5, IL-6, CXCL8 (IL-8), IL-10, IL-13 occurring in plasma of healthy blood donors

Mediators of Inflammation, 2006
Background. The cytokine network remarkably influences homeostasis. There is not a complex analysis describing physiological values of soluble cytokines in healthy individuals. Methods.
Klabusay Martin, Kohutova Viera, Coupek Petr, Nenickova Marie, Tesarova Eva   +4 more
doaj   +1 more source

Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry

Frontiers in Immunology, 2019
Canonical inflammasome activation is a tightly regulated process that has been implicated in a broad spectrum of inflammatory disorders. Inflammasome formation requires assembly of a cytosolic sensor protein with the adapter, ASC (apoptosis-associated ...
Silvia Lucena Lage, Venina Marcela Dominical, Chun-Shu Wong, Irini Sereti   +3 more
doaj   +1 more source

Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

Nature Communications, 2019
Natural killer (NK) cells are important innate immune cells with diverse functions. Here the authors use single-cell RNA-sequencing of purified human bone marrow and peripheral blood NK cells to define five populations of NK cells with distinct ...
Chao Yang, Jason R. Siebert, Robert Burns, Zachary J. Gerbec, Benedetta Bonacci, Amy Rymaszewski, Mary Rau, Matthew J. Riese, Sridhar Rao, Karen-Sue Carlson, John M. Routes, James W. Verbsky, Monica S. Thakar, Subramaniam Malarkannan   +13 more
doaj   +1 more source

Altered hippocampal function in major depression despite intact structure and resting perfusion [PDF]

, 2016
Background: Hippocampal volume reductions in major depression have been frequently reported. However, evidence for functional abnormalities in the same region in depression has been less clear.
A. Finkelmeyer, Campbell, Della Sala, Golden, I. N. Ferrier, J. He, J. J. Maller, J. Nilsson, K. Coventry, L. Stevens, McKinnon, Nelson, P. Gallagher, R. A. Moss, R. H. McAllister-Williams, S. Small, Schmidt, Sheehan, Spielberger   +18 more
core   +2 more sources

In vivo effects of horse and rabbit antithymocyte globulin in patients with severe aplastic anemia

Haematologica, 2014
We recently reported that rabbit antithymocyte globulin was markedly inferior to horse antithymocyte globulin as a primary treatment for severe aplastic anemia. Here we expand on our findings in this unique cohort of patients.
Xingmin Feng, Phillip Scheinberg, Angelique Biancotto, Olga Rios, Sarah Donaldson, Colin Wu, Haiyun Zheng, Kazuya Sato, Danielle M. Townsley, J. Philip McCoy, Neal S. Young   +10 more
doaj   +1 more source

Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature

eLife, 2020
The transcriptional activation and repression during NK cell ontology are poorly understood. Here, using single-cell RNA-sequencing, we reveal a novel role for T-bet in suppressing the immature gene signature during murine NK cell development.
Chao Yang, Jason R Siebert, Robert Burns, Yongwei Zheng, Ao Mei, Benedetta Bonacci, Demin Wang, Raul A Urrutia, Matthew J Riese, Sridhar Rao, Karen-Sue Carlson, Monica S Thakar, Subramaniam Malarkannan   +12 more
doaj   +1 more source

Dehydration accelerates reductions in cerebral blood flow during prolonged exercise in the heat without compromising brain metabolism [PDF]

, 2015
Dehydration hastens the decline in cerebral blood flow (CBF) during incremental exercise, while the cerebral metabolic rate for oxygen (CMRO2) is preserved.
Benjamin Garcia, Gibbs EL, Iñaki Llodio, Johnson JM, José González-Alonso, Kameljit K. Kalsi, Niels H. Secher, Scott T. Chiesa, Steven J. Trangmar   +8 more
core   +2 more sources

Glutamate load fosters spreading depolarization under osmotic stress in brain slices

Frontiers in Cellular Neuroscience
IntroductionCerebral edema is a hallmark of lesion progression after acute ischemic stroke (AIS) and a major contributor to the evolution of spreading depolarizations (SDs). SDs trigger extracellular glutamate accumulation and excitotoxic injury, yet the
Rita Frank, Rita Frank, Stephane Marinesco, Ferenc Bari, Ákos Menyhárt, Ákos Menyhárt, Eszter Farkas, Eszter Farkas   +7 more
doaj   +1 more source