Results 21 to 30 of about 6,939,165 (291)

Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B1

Molecular Oncology, 2023
Mutations in the splicing factor 3b subunit 1 (SF3B1) gene are frequent in myelodysplastic neoplasms (MDS). Because the splicing process is involved in the production of circular RNAs (circRNAs), we investigated the impact of SF3B1 mutations on circRNA ...
Iva Trsova, Andrea Hrustincova, Zdenek Krejcik, David Kundrat, Aleš Holoubek, Karolina Staflova, Lucie Janstova, Sarka Vanikova, Katarina Szikszai, Jiri Klema, Petr Rysavy, Monika Belickova, Monika Kaisrlikova, Jitka Vesela, Jaroslav Cermak, Anna Jonasova, Jiri Dostal, Jan Fric, Jan Musil, Michaela Dostalova Merkerova   +19 more
doaj   +1 more source

Prediction model for the risk of ischemic recurrence in symptomatic severe intracranial vertebrobasilar artery stenosis

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To identify the risk factors associated of ischemic recurrence in patients with chronic symptomatic severe intracranial vertebrobasilar artery stenosis and to establish a corresponding risk prediction model (Nomogram model).
LI Qi, SUN Yang, ZHANG Meng, TONG Xiao-guang   +3 more
doaj   +1 more source

Progress on the application of deep brain stimulation in refractory mental disease

Chinese Journal of Contemporary Neurology and Neurosurgery
Deep brain stimulation (DBS), a reversible and adjustable neuromodulation technique, has expanded from its initial application in movement disorders to the treatment of mental disease.
WU Jing-chao, LIANG Si-quan
doaj   +1 more source

Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease [PDF]

, 2012
A nitric oxide synthase (NOS)-like activity has been demonstrated in human red blood cells (RBCs), but doubts about its functional significance, isoform identity and disease relevance remain.
Rodriguez-Mateos, Ana; id_orcid, Wolters, Dirk, Heiß, Christian, Rodriguez Mateos, Ana, Krenz, Thomas, Kuhnle, G. G. C., Cortese-Krott, Miriam M, Rodriguez-Mateos, Ana, Kelm, Malte, Cortese-Knott, Miriam M., Feelisch, Martin, Rodriguez-Mateos, Z, Kroncke, K.-D., Kröncke, Klaus-Dietrich, Sansone, R., Kuhnle, Gunter G. C., Kelm, M., Heiss, C., Krisp, C., Sansone, Roberto, Horn, P., Feelisch, M., Horn, Patrick, Krisp, Christoph, Krenz, T., Hogg, N., Kuhnle, Gunter, Kuhnle, Gunter G.C., Thasian-Sivarajah, S., Thasian-Sivarajah, Sivatharsini, Wolters, D., Cortese-Krott, Miriam M., Hogg, Neil, Cortese-Krott, M. M.   +33 more
core   +1 more source

Determination of regional bone blood flow by means of fluorescent microspheres using an automated sample-processing procedure [PDF]

, 2003
The determination of regional blood flow utilizing fluorescent microspheres (FMs) is an established method for numerous organs. Recent progress, in particular the automation of sample processing, has further improved this method.
Thein, E., Walli, A. K., Anetzberger, H., Messmer, K., Anetzberger, H;Thein, E;Walli, AK;Messmer, K   +4 more
core   +1 more source

Analyzing the involvement of diverse cell death-related genes in diffuse large B-cell lymphoma using bioinformatics techniques

Heliyon
Diffuse large B-cell lymphoma (DLBCL) stands as the most prevalent subtype of non-Hodgkin's lymphoma and exhibits significant heterogeneity. Various forms of programmed cell death (PCD) have been established to have close associations with tumor onset ...
Heyuan Feng, Xiyuan Zhang, Jian Kang
doaj   +1 more source

Nomogram for the prediction of surgical site infection following spinal surgery: a multicenter retrospective study

Frontiers in Medicine
ObjectiveSurgical site infection (SSI) represents a prevalent postoperative complication associated with spinal surgery, contributing to increased morbidity and mortality rates.
Yang Sun, Yang Sun, Yang Sun, Qi Li, Qi Li, Qi Li, Pengfei Zhai, Pengfei Zhai, Pengfei Zhai, Rui Zhang, Hongguang Wang, Hongguang Wang, Hongguang Wang, Xiaoguang Tong, Xiaoguang Tong, Xiaoguang Tong   +15 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Non-invasive preoperative MRI-based deep transfer learning radiomics model for predicting meningioma brain invasion

Frontiers in Oncology
BackgroundCurrent preoperative assessment of meningioma brain invasion (BI) demands imaging analytical frameworks that optimize computational efficiency while capturing multidimensional tumor-pathology correlations.
Dong Yuan, Dong Yuan, Dong Yuan, Jiajia Zhang, Jiajia Zhang, Chao Zhang, Chao Zhang, Xiyue Jing, Quanzhi Feng, Tong Han, Tong Han   +10 more
doaj   +1 more source