Results 11 to 20 of about 1,629,049 (268)

TIGIT-positive circulating follicular helper T cells display robust B-cell help functions: potential role in sickle cell alloimmunization

Haematologica, 2015
T follicular helper cells are the main CD4+ T cells specialized in supporting B-cell responses, but their role in driving transfusion-associated alloimmunization is not fully characterized.
Emmanuelle Godefroy, Hui Zhong, Petra Pham, David Friedman, Karina Yazdanbakhsh   +4 more
doaj   +1 more source

Immune cell phenotyping in low blood volumes for assessment of cardiovascular disease risk, development, and progression: a pilot study

Journal of Translational Medicine, 2020
Background Cardiovascular disease (CVD) is the leading cause of death in the world. Given the role of immune cells in atherosclerosis development and progression, effective methods for characterizing immune cell populations are needed, particularly among
Yvonne Baumer, Cristhian A. Gutierrez-Huerta, Ankit Saxena, Pradeep K. Dagur, Steven D. Langerman, Kosuke Tamura, Joniqua N. Ceasar, Marcus R. Andrews, Valerie Mitchell, Billy S. Collins, Quan Yu, Heather L. Teague, Martin P. Playford, Christopher K. E. Bleck, Nehal N. Mehta, J. Philip McCoy, Tiffany M. Powell-Wiley   +16 more
doaj   +1 more source

Subcutaneous immunotherapy induces alterations in monocytes and dendritic cells homeostasis in allergic rhinitis patients

Allergy, Asthma & Clinical Immunology, 2018
Background Specific subcutaneous immunotherapy (SCIT) can achieve long-term remission in patients with allergic rhinitis (AR) through complex and still unknown mechanisms.
Letícia Sousa, Carmen Martín-Sierra, Celso Pereira, Graça Loureiro, Beatriz Tavares, Susana Pedreiro, António Martinho, Artur Paiva   +7 more
doaj   +1 more source

Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B1

Molecular Oncology, 2023
Mutations in the splicing factor 3b subunit 1 (SF3B1) gene are frequent in myelodysplastic neoplasms (MDS). Because the splicing process is involved in the production of circular RNAs (circRNAs), we investigated the impact of SF3B1 mutations on circRNA ...
Iva Trsova, Andrea Hrustincova, Zdenek Krejcik, David Kundrat, Aleš Holoubek, Karolina Staflova, Lucie Janstova, Sarka Vanikova, Katarina Szikszai, Jiri Klema, Petr Rysavy, Monika Belickova, Monika Kaisrlikova, Jitka Vesela, Jaroslav Cermak, Anna Jonasova, Jiri Dostal, Jan Fric, Jan Musil, Michaela Dostalova Merkerova   +19 more
doaj   +1 more source

Progress on the application of deep brain stimulation in refractory mental disease

Chinese Journal of Contemporary Neurology and Neurosurgery
Deep brain stimulation (DBS), a reversible and adjustable neuromodulation technique, has expanded from its initial application in movement disorders to the treatment of mental disease.
WU Jing-chao, LIANG Si-quan
doaj   +1 more source

Blood flow in glaucoma [PDF]

British Journal of Ophthalmology, 2006
Glaucoma: a vascular dysregulation Increased cupping of the optic nerve head, a result of progressive loss of the retinal nerve fibres and remodelling of the supporting connective tissue in and around the lamina cribrosa, characterises glaucomatous optic neuropathy. Although reducing intraocular pressure represents a relevant approach in the treatment
openaire   +2 more sources

Analyzing the involvement of diverse cell death-related genes in diffuse large B-cell lymphoma using bioinformatics techniques

Heliyon
Diffuse large B-cell lymphoma (DLBCL) stands as the most prevalent subtype of non-Hodgkin's lymphoma and exhibits significant heterogeneity. Various forms of programmed cell death (PCD) have been established to have close associations with tumor onset ...
Heyuan Feng, Xiyuan Zhang, Jian Kang
doaj   +1 more source

Nomogram for the prediction of surgical site infection following spinal surgery: a multicenter retrospective study

Frontiers in Medicine
ObjectiveSurgical site infection (SSI) represents a prevalent postoperative complication associated with spinal surgery, contributing to increased morbidity and mortality rates.
Yang Sun, Yang Sun, Yang Sun, Qi Li, Qi Li, Qi Li, Pengfei Zhai, Pengfei Zhai, Pengfei Zhai, Rui Zhang, Hongguang Wang, Hongguang Wang, Hongguang Wang, Xiaoguang Tong, Xiaoguang Tong, Xiaoguang Tong   +15 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source