ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Response: Commentary: Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety. [PDF]
Kambic T, Jug B, Lainscak M.
europepmc +1 more source
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
Brachial artery flow-mediated dilatation (BAFMD) is an endothelium-dependant and nitric oxide specific index of endothelial function. The chronic effect of isometric exercise on endothelial function remains equivocal.
Wiles, J., Howland, L., Coleman, D.
core
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Blood Flow Restriction Hemodynamics (BFRH)
Inflating a pneumatic cuff around the proximal portion of an exercising limb – known as ‘blood flow restriction’ (BFR) – can induce significant muscular adaptations even at low exercise intensities.
Michael Tschakovsky, Stuart Mladen
core +1 more source
Beneficial Role of Blood Flow Restriction Exercise in Heart Disease and Heart Failure Using the Muscle Hypothesis of Chronic Heart Failure and a Growing Literature. [PDF]
Cahalin LP +4 more
europepmc +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source
Effects of Blood Flow Restriction Exercise on Muscle Oxygenation and Microvascular Function in Healthy Individuals: A Narrative Review. [PDF]
Gakidi A +7 more
europepmc +1 more source
ADAPTations to low load blood flow restriction exercise versus conventional heavier load resistance exercise in UK military personnel with persistent knee pain: protocol for the ADAPT study, a multi-centre randomized controlled trial. [PDF]
Cassidy RP +9 more
europepmc +1 more source

