Results 31 to 40 of about 1,194,803 (309)

The Effects of Involuntary Respiratory Contractions on Cerebral Blood Flow during Maximal Apnoea in Trained Divers. [PDF]

PLoS ONE, 2013
The effects of involuntary respiratory contractions on the cerebral blood flow response to maximal apnoea is presently unclear. We hypothesised that while respiratory contractions may augment left ventricular stroke volume, cardiac output and ultimately ...
Troy J Cross, Justin J Kavanagh, Toni Breskovic, Petra Zubin Maslov, Mihajlo Lojpur, Bruce D Johnson, Zeljko Dujic   +6 more
doaj   +1 more source

Excess pressure as an analogue of blood flow velocity

Journal of Hypertension, 2020
Introduction: Derivation of blood flow velocity from a blood pressure waveform is a novel technique, which could have potential clinical importance. Excess pressure, calculated from the blood pressure waveform via the reservoir-excess pressure model, is purported to be an analogue of blood flow velocity but this has never been ...
Armstrong, MK, Schultz, MG, Hughes, AD, Picone, DS, Black, JA, Dwyer, N, Roberts-Thomson, P, Sharman, JE   +7 more
openaire   +4 more sources

Transcutaneous measurement of blood velocity profiles and flow [PDF]

Cardiovascular Research, 1973
A comprehensive report is presented of the application of a pulsed ultrasound Doppler velocity meter for transcutaneous measurement of time varying velocity, velocity profiles, and instantaneous flow in arteries of anaesthetized dogs. The procedure used to provide direct velocity and flow calibration using the Doppler equation is outlined.
Histand, Michael B, Miller, Charles W, McLeod, Francis D   +2 more
openaire   +3 more sources

Quantification of leptomeningeal collateral blood flow in hypertensive rats during ischemic stroke

Journal of Stroke and Cerebrovascular Diseases
Objectives: There is increasing evidence that poor leptomeningeal collateral blood flow in hypertensive animals is due to increased vascular myogenic tone, indicating that therapies to enhance collateral blood flow during ischemic stroke may be ...
Magdalena Litman, MPharm, Kristy Martin, BSc (Hons), Neil J Spratt, FRACP, PhD, Daniel J Beard, PhD   +3 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Evaluation of arterial digital blood flow using Doppler ultrasonography in healthy dairy cows

BMC Veterinary Research, 2017
Background Local circulatory disturbances have been implicated in the development of foot disorders in cattle. The goals of this study were to evaluate the suitability of the interdigital artery in the pastern region in both hind limbs using pulsed-wave (
H. Müller, M. Heinrich, N. Mielenz, S. Reese, A. Steiner, A. Starke   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Preoperative Femoral Vein Velocity in Maximal Flexion Is a Predictor of Deep Vein Thrombosis in Patients Undergoing Total Hip Arthroplasty

Acta Clinica Croatica, 2020
The aim of the study was to investigate if preoperative blood flow velocity in femoral vein in different positions of the hip during total hip arthroplasty (THA) is a predictor of postoperative deep vein thrombosis (DVT).
Amel Hadžimehmedagić, Bekir Rovčanin, Haris Vranić, Muhamed Djedović, Slavenka Štraus, Tarik Selimović   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source