Results 41 to 50 of about 4,921,470 (255)

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Enhanced biodegradation of polyaromatic hydrocarbons in manufactured gas plant wastes [PDF]

, 1990
Scientists at the Institute of Gas Technology (IGT) have focused on enhancing destruction of polyaromatic hydrocarbons (PAHs) present as pollutants in manufactured gas plant (MGP) soils.
Gauger, W.K., Hayes, T.D., Srivastava, V.J. (Institute of Gas Technology, Chicago, IL (United States)), Linz, D.G. (Gas Research Inst., Chicago, IL (United States))   +3 more
core  

Blood gas results.

, 2015
Arterial and mixed venous blood gas results.Blood gas results.
Christian Neuhaus (745048), Wolfgang Dersch (745053), Karl Kesper (745051), Clemens Kill (745046), Monika Galbas (745047), Hinnerk Wulf (745052), Pascal Wallot (745050), Oliver Hahn (745049)   +7 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Development of natural gas reburning for control of NO sub x from municipal waste combustors [PDF]

, 1991
The Gas Research Institute (GRI) and the Institute of Gas Technology (IGT), in cooperation with Riley Stoker Corporation (Riley), USA, and Takuma Company Ltd.
Abbasi, H., Tarman, P.B. (Institute of Gas Technology, Chicago, IL (United States)), Linz, D.G. (Gas Research Inst., Chicago, IL (United States))   +2 more
core  

Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood

, 2010
Here we report the first application of a fractal analysis of the viscoelastic properties of incipient blood clots. We sought to ascertain whether the incipient clot's fractal dimension, Df, could be used as a functional biomarker of hemostasis.
Karl Hawkins, Rhodri Williams, Matthew Lawrence, Lisa Wakeman, Matthew J. Lawrence, Phillip A. Evans, Roger Munro, Adrian Evans, P. Rhodri Williams, Naresh Thirumalai, Roger H. K. Morris   +10 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Arterial blood analysis of healthy residents in Huamachuco, Peru (3,164 m): a cross-sectional study [version 2; peer review: 2 approved, 1 not approved]

F1000Research, 2023
Background: Given that arterial blood gas is affected by altitude and ethnicity, establishing reliable reference standards for these values requires analysis of arterial blood at different elevations and locations.
Lissett J. Fernández-Rodríguez, Cecilia Romero-Goicochea, Victor H. Bardales-Zuta   +2 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source