Results 1 to 10 of about 249,255 (314)

Angiotensin 1-7 and losartan worsen the cisplatin induced nephrotoxicity in female rats [PDF]

open access: yesJournal of Nephropharmacology, 2022
Introduction: Cisplatin (CP) is an anti-cancer drug with the most common side effects of nephrotoxicity. Losartan, an angiotensin II type 1 receptor (AT1R) antagonist and angiotensin 1-7 (Ang1-7) protects the kidney against CP administration in males ...
Sayyedehnikta Kasaei   +6 more
doaj   +1 more source

Electrospun polymer nanofibers: the booming cutting edge technology [PDF]

open access: yes, 2012
Electrospinning has been recognized as a simple and efficient technique for the fabrication of ultrathin fibers from a variety of materials including polymers, composite and ceramics.
Lim, Du-Hyun   +6 more
core   +4 more sources

Intravenous Administration of Cisplatin with Magnesium Sulfate Supplement May Prevent Kidney Toxicity in Rats: The Role of Gender and Magnesium Sulfate Dose

open access: yesInternational Journal of Nephrology, 2022
Background. Cisplatin (CP) is widely used to treat various kinds of malignancies, but to avoid its side effects of nephrotoxicity and hypomagnesemia, magnesium supplementation is a subject of debate.
Parisa Pournaderi   +5 more
doaj   +1 more source

Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors

open access: yesInternational Journal of Nephrology, 2022
The sympathetic and renin-angiotensin systems (RAS) are two critical regulatory systems in the kidney which affect renal hemodynamics and function. These two systems interact with each other so that angiotensin II (Ang II) has the presynaptic effect on ...
Hajaralsadat Hosseini-Dastgerdi   +3 more
doaj   +1 more source

Hydration with Mannitol and Dextrose May Promote Cisplatin-Induced Nephrotoxicity: Test of Five Protocols of Hydration during Cisplatin Therapy in Rat Models

open access: yesJournal of Toxicology, 2021
Backgrounds. Cisplatin (CP) still is a novel choice for solid tumor therapy, but it is accompanied with the side effect of nephrotoxicity. Hydration may reduce the risk of CP-induced nephrotoxicity, while the issue is still challenging.
Mohammad-Sedigh Khosravi   +5 more
doaj   +1 more source

High Entropy Electrolytes for Practical Lithium Metal Batteries [PDF]

open access: yes, 2023
Electrolyte engineering is crucial for improving battery performance, particularly for lithium metal batteries. Recent advances in electrolytes have greatly improved cyclability by enhancing electrochemical stability at the electrode interfaces, but ...
Yi, Cui   +17 more
core   +2 more sources

Time course of cisplatin-induced nephrotoxicity and hepatotoxicity [PDF]

open access: yesJournal of Nephropathology, 2017
Background: One of the main therapeutic limitations of cisplatin (CP) is nephrotoxicity which is time-dependent. Objectives: The purpose of this study was to determine the optimal timing for initiation of CP toxicity.
Zahra Pezeshki   +8 more
doaj   +1 more source

Effect of pomegranate flower extract on cisplatin-induced nephrotoxicity in rats [PDF]

open access: yesJournal of Nephropathology, 2014
Background: Chemotherapy with cisplatin (CP) is accompanied with nephrotoxicity. Objectives: In the current study, pomegranate flower extract (PFE) has been evaluated as an antioxidant agent against CP-induced-renal toxicity.
Fatemeh Motamedi   +9 more
doaj   +1 more source

Role of endothelin receptor antagonist; bosentan in cisplatin-induced nephrotoxicity in ovariectomized estradiol treated rats [PDF]

open access: yesJournal of Nephropathology, 2015
Background: Endothelin-1 (ET-1) is a vasoconstrictor peptide that mediates cell proliferation, fibrosis, and inflammation. ET-1 has 2 receptors A and B. Objectives: The present study investigated whether administration of ET-1 receptor type A antagonist
Alieh Zahedi   +3 more
doaj   +1 more source

Sex Difference in Cisplatin-Induced Nephrotoxicity: Laboratory and Clinical Findings

open access: yesJournal of Toxicology, 2022
Cisplatin (CP) as the most important anticancer drug has limited usage due to a lot of side effects such as nephrotoxicity. Additionally, nephrotoxicity is gender/sex-related.
Fatemeh Eshraghi-Jazi, Mehdi Nematbakhsh
doaj   +1 more source

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