Results 41 to 50 of about 1,368,531 (297)

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Blood Glucose Levels during Decathlon Competition: An Observational Study in Timing of Intake and Competing Time

Metabolites
During a men’s decathlon, a combined event conducted over two consecutive days, fluctuations in blood glucose were measured using flash glucose monitoring. Because decathletes repeatedly intake and exercise, high and low blood glucose levels are observed,
Rikako Yoshitake, Hitomi Ogata, Naomi Omi   +2 more
doaj   +1 more source

Teaching Casual Random Blood Glucose Screening to Second-Year Dental Students [PDF]

, 2009
In our project, archived casual random blood glucose levels of second-year dental students who were taught the mechanics of self-testing were retrieved.
Kassab, Moawi M, Lynch, Denis P, Radmer, Thomas W, Walsh, Martin   +3 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

High-normal blood glucose levels may be associated with decreased spatial perception in young healthy adults. [PDF]

, 2018
The negative effects of high normal glucose on cognitive function were previously reported in euglycemic individuals of middle age and the elderly population.
A Boehmer, A Kemeny, A Simmons, AB Scholey, Abdulla Faisal Alshaiji, Abdulrahman Ahmed Qareeballa, AC Guyton, C Lopez, C Messier, FW Akin, G Mazibrada, H Nyborg, H Nyborg, J Bagust, J Bagust, J Bagust, J Bagust, J Cohen, J Waterhouse, JE Sprague, Jeff Bagust, JS Durmer, K Murray, K Noriaki, L Kerti, LC Perlmuter, M Reivich, ME Mortby, MMK Hijazi, Mohamed Wael Mohamed, N Cherbuin, PK Crane, R Abdul Razzak, R Nakashima, R Roky, R Roky, RAA Vingerhoets, Rima Abdul Razzak, RJ McCrimmon, RT Donohoe, S Docherty, S Fitzgerald, S Fitzgerald, Sharon Docherty, Stephen L. Atkin, T Reilly, T Romeas   +46 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

The Antidiabetic Activity of Curry Leaves “Murraya Koenigii” on the Glucose Levels, Kidneys, and Islets of Langerhans of Rats with Streptozotocin Induced Diabetes [PDF]

, 2017
Background: The aims of this study were to explore the antihyperglycemic effect of curry leaves, Murraya koenigii "MK" aqueous extract, and to examine its possible protective effects on the islets of Langerhans and kidneys of streptozotocin (STZ ...
Al-Ani, I. M. (Imad), Alazzawi, K. S. (Khalid), Santosa, R. I. (Rahajoe), Saxena, A. K. (Anil), Yankuzo, M. H. (Muhammad)   +4 more
core