Results 71 to 80 of about 3,071,300 (338)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

UJI AKTIVITAS EKSTRAK ETANOL BUAH PARE (Momordica charantia L.) TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA MENCIT PUTIH JANTAN

JIIS: Jurnal Ilmiah Ibnu Sina, 2018
Degenerative disease is a disease that causes damage or destruction of tissues or organs of the body due to unhealthy lifestyle where one of them is diabetes mellitus disease.
Aditya Maulana Perdana Putra, Ratih Pratiwi Sari   +1 more
doaj  

High levels of blood lipid and glucose predict adverse prognosis in patients with aneurysmal subarachnoid hemorrhage

Heliyon
Objective: We conducted a retrospective study on the prognostic factors of aneurysmal subarachnoid hemorrhage (aSAH) patients in the author's Hospital from January 2019 to May 2023.
Zhu Yajun, Ouyang Diqing, Lei Xingwei, Tang Liuyang, Zhang Xiaofeng, Li Xiaoguo, Guo Zongduo   +6 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]

, 2016
Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Albert V, Christoph Handschin, Fatima Bosch, Greco‐Perotto R, Hao Q, Kristoffer Svensson, Marco Colombi, Michael N Hall, Mitsugu Shimobayashi, Sergio Muñoz, Vallerand AL, Verena Albert, Veronica Jimenez   +12 more
core   +4 more sources

Breath Acetone-Based Non-Invasive Detection of Blood Glucose Levels

, 2015
There has been a constant demand for the development of non-invasive, sensitive glucose sensor system that offers fast and real-time electronic readout of blood glucose levels.
Anand Thati, Arunangshu Biswas, S. Chowdhury, T. Sau   +3 more
semanticscholar   +1 more source

Low-cost portable microwave sensor for non-invasive monitoring of blood glucose level: novel design utilizing a four-cell CSRR hexagonal configuration

Scientific Reports, 2020
This article presents a novel design of portable planar microwave sensor for fast, accurate, and non-invasive monitoring of the blood glucose level as an effective technique for diabetes control and prevention.
Ala Eldin Omer, G. Shaker, S. Safavi-Naeini, H. Kokabi, G. Alquié, F. Deshours, R. Shubair   +6 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Antidiabetic Activity From Ethanol Extract of Kluwih's Leaf (Artocarpus Camansi) [PDF]

, 2011
Research on antidiabetic activity of ethanol leaf extracts Kluwih (Artocarpus camansi) has been carried out to determine the antidiabetic activity of ethanol extract of leaves kluwih (EELK) of mice using glucose tolerance test.
Marianne, M. (Marianne), Rosnani, R. (Rosnani), Yuandani, Y. (Yuandani)   +2 more
core  

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source