Results 151 to 160 of about 863,756 (239)

Polyanhydride‐Based Microparticles for Programmable Pulsatile Release of Diphtheria Toxoid (DT) for Single‐Injection Self‐Boosting Vaccines

Advanced Materials, EarlyView.
This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Linzixuan Zhang, Ruiqing Xiao, Wenhao Gao, Johnny Garcia, Xinyan Pan, John L. Daristotle, Timothy Forster, Jooli Han, Mehr Chaddah, Dhruv Varshney, Nandita Menon, Kevin J. McHugh, Benjamin J. Pedretti, Jing Ying Yeo, Xin Yang, Sydney MacDonald, Robert Langer, Ana Jaklenec   +17 more
wiley   +1 more source

Human Norovirus Histo-Blood Group Antigen (HBGA) Binding Sites Mediate the Virus Specific Interactions with Lettuce Carbohydrates. [PDF]

Viruses, 2019
Esseili MA, Gao X, Boley P, Hou Y, Saif LJ, Brewer-Jensen P, Lindesmith LC, Baric RS, Atmar RL, Wang Q.   +9 more
europepmc   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Effects of Child and Maternal Histo-Blood Group Antigen Status on Symptomatic and Asymptomatic Enteric Infections in Early Childhood. [PDF]

J Infect Dis, 2019
Colston JM, Francois R, Pisanic N, Peñataro Yori P, McCormick BJJ, Olortegui MP, Gazi MA, Svensen E, Ahmed MMM, Mduma E, Liu J, Houpt ER, Klapheke R, Schwarz JW, Atmar RL, Black RE, Kosek MN.   +16 more
europepmc   +1 more source

Ionic Liquid‐Reinforced Multifunctional Hydrogel for the Treatment of Enterocutaneous Fistula

Advanced Materials, EarlyView.
ECFGel is a multifunctional hydrogel engineered to treat infection‐associated ECFs. ECFGel demonstrates outstanding mechanical and biological properties, facilitating easy application, reliable occlusion, and sterilization, while promoting effective healing of infected fistula tracts.
Jinjoo Kim, Hyeongseop Keum, Hassan Albadawi, Ismail Altinbasak, Furkan Yavuz, Erin H. Graf, Nitin Mishra, Rahmi Oklu   +7 more
wiley   +1 more source

Histo-blood group antigen-binding specificities of human rotaviruses are associated with gastroenteritis but not with in vitro infection. [PDF]

Sci Rep, 2018
Barbé L, Le Moullac-Vaidye B, Echasserieau K, Bernardeau K, Carton T, Bovin N, Nordgren J, Svensson L, Ruvoën-Clouet N, Le Pendu J.   +9 more
europepmc   +1 more source

Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance

Advanced Materials, EarlyView.
This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee, Heung Jin Jeon, Dohyub Jang, Deukhee Lee, Solbi Kim, Minju Han, Sharon Jiyoon Jung, Jung‐Hyun Lee, Jia Choi, Dong Ha Kim, Dong June Ahn, Keri Kim, Sehoon Kim, Hyo‐Jin Lee, SeungBeum Suh   +14 more
wiley   +1 more source

Quantifying the binding stoichiometry and affinity of histo-blood group antigen oligosaccharides for human noroviruses. [PDF]

Glycobiology, 2018
Han L, Zheng R, Richards MR, Tan M, Kitova EN, Jiang X, Klassen JS.   +6 more
europepmc   +1 more source

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

Advanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash, Waleed M. Hussein, Ummey J. Nahar, Jingwen Wang, Lantian Lu, Armira Azuar, Jolynn J. E. Kiong, Prashamsa Koirala, Zeinab G. Khalil, Istvan Toth   +9 more
wiley   +1 more source

HLA and Histo-Blood Group Antigen Expression in Human Pluripotent Stem Cells and their Derivatives. [PDF]

Sci Rep, 2017
Säljö K, Barone A, Mölne J, Rydberg L, Teneberg S, Breimer ME.   +5 more
europepmc   +1 more source