Results 241 to 250 of about 1,450,892 (352)

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Quantifying the binding stoichiometry and affinity of histo-blood group antigen oligosaccharides for human noroviruses. [PDF]

Glycobiology, 2018
Han L, Zheng R, Richards MR, Tan M, Kitova EN, Jiang X, Klassen JS.   +6 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

HLA and Histo-Blood Group Antigen Expression in Human Pluripotent Stem Cells and their Derivatives. [PDF]

Sci Rep, 2017
Säljö K, Barone A, Mölne J, Rydberg L, Teneberg S, Breimer ME.   +5 more
europepmc   +1 more source

A, B, H, and Lewis-a and Lewis-b blood group antigens in human breast cancer: Correlation with steroid hormone receptor and disease status

, 1993
Halliday Idikio, V. Manickavel
openalex   +2 more sources

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

The influence of HK2 blood group antigen on human B cell activation for ABOi-KT conditions. [PDF]

BMC Immunol, 2017
Cao J, Liu L, Zhang Y, Xiao J, Wang Y.
europepmc   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Targeted breast cancer therapy by harnessing the inherent blood group antigen immune system. [PDF]

Oncotarget, 2017
Han W, Li W, Zhang X, Du Z, Liu X, Zhao X, Wen X, Wang G, Hu JF, Cui J.   +9 more
europepmc   +1 more source

An Approach Using PSA Levels of 1.5 ng/mL as the Cutoff for Prostate Cancer Screening in Primary Care. [PDF]

, 2016
Arangua, Paul, Carroll, Peter, Cooperberg, Matthew R., Crawford, E. David, Eastham, James, Gomella, Leonard G., Hoenemeyer, John, Klein, Eric A., Leapman, Michael, Leveridge, Mike, Loeb, Stacy, Maccini, Michael, Partin, Alan W., Pettaway, Curtis A., Pinto, Peter, Rosenberg, Matt T., Shore, Neal D., Thompson, Ian M.   +17 more
core   +2 more sources