Results 291 to 300 of about 1,450,892 (352)

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Blood group reckoning: Unraveling the mystery of blood group antigens: Blood group reckoning

Annals of Medical Physiology, 2018
openaire   +1 more source

[Immunization against blood group antigens].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1968
openaire   +1 more source

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ABO blood groups and Australia antigen

Clinical Genetics, 1974
The distribution of ABO blood in two groups of people with Australia antigen was studied (121 blood donors and 128 patients) and in 3,091 controls was investigated. There was a significant excess of A in comparison with o when the two groups were combined, and when the two groups were tested for (A + B): (AB +O) individually and together, both were ...
A, Arndt-Hanser, R, Ananthakrishnan, H, Walter   +2 more
openaire   +2 more sources

Blood Group Antigens: Blood Group Carbohydrate Antigens

2009
The most popular blood group antigen system, ABO antigens had been known to consist of alpha1,2-fucosylated galactose substituted with alpha1,3-N-acetylgalactosamine (A) or galactose (B). These biochemical results were clearly confirmed and further investigated by the molecular cloning of blood group A synthase cDNA (Yamamoto et al. 1990a, 1990b).
Koichi Furukawa, Koichi Iwamura, Keiko Furukawa   +2 more
openaire   +1 more source

The Rare Blood Group Antigen, Wu

Vox Sanguinis, 1976
Abstract. The inheritance of the Wu antigen in three families is described. The observations suggest that the antigen is inherited as a Mendelian dominant character. Wu segregates independently of sex and of the ABO, MNSs, Rh, Lutheran, Duffy and Kidd blood group systems. Independence of Kell is also quite likely. Wu is a very rare antigen.
L, Kronstad, P, Howell, J, Jorgensen, A M, Larsen, L D, Wadsworth   +4 more
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A New Blood Group Antigen, Hov

Vox Sanguinis, 1973
Abstract. A new blood group antigen, Hov, is described. The antigen is not closely linked to the MNSs, P, Rhesus secretor, Duffy and Kidd loci, and it is not X‐linked. 1,155 blood samples were tested; two of these had the new antigen.
A, Szaloky, N K, Sijpesteijn, , Hart M vander   +2 more
openaire   +2 more sources

Biologic functions of blood group antigens

Current Opinion in Hematology, 1996
In the past few years, we have learned a great deal about the biologic function of structures bearing blood group antigens. Some blood group antigen-bearing proteins function as major transport channels within the erythrocyte membrane; these include the anion transporter (band 3: Diego and Wright antigens), the water channel (aquaporin: Colton antigens)
R, Mudad, M J, Telen
openaire   +2 more sources

Monoclonal Antibodies against Blood Group Antigens

1984
Monoclonal anti-A, anti-B, anti-H antibodies have been produced by a murine hybridoma. C57BL/6 mice have been immunized by different red blood cells. The main characteristics of these antibodies are the following: specificity: anti-A agglutination only A cells, including A2, A3, Ax (from a panel of 50 cells); anti-B agglutinates only B cells (B3, Bx ...
L, Edelman, J F, Bach, J, Reviron
openaire   +2 more sources