Results 141 to 150 of about 7,093,189 (263)

Lead and Mortality [PDF]

This paper examines the effect of water-borne lead exposure on infant mortality in American cities over the period 1900-1920. Infants are highly sensitive to lead, and more broadly are a marker for current environmental conditions. The effects of lead on
Michael R. Haines, Karen Clay, Werner Troesken   +2 more
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Blood Lead Testing Among Children Enrolled in Medicaid. [PDF]

Pediatrics
Cornwell CR, Pennington AF, Williams T, Ruckart PZ, Courtney JG, Allwood P.   +5 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Environmental Policy as Social Policy? The Impact of Childhood Lead Exposure on Crime [PDF]

Childhood lead exposure can lead to psychological deficits that are strongly associated with aggressive and criminal behavior. In the late 1970s in the United States, lead was removed from gasoline under the Clean Air Act.
Jessica Wolpaw Reyes
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Sample-to-Answer Point-of-Care Blood Lead Level Test. [PDF]

Biosensors (Basel)
Warren RL, Pueschel AR, Yu WW, White IM.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Blood Lead Reference Value [PDF]

CDC uses a blood lead reference value (BLRV) of 3.5 micrograms per deciliter (\ub5g/dL) to identify children with blood lead levels that are higher than most children\u2019s levels.CDC\u2019s Blood Lead Reference ValueIn 2012, the Centers for Disease ...

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Workers' Behavior and Hygienic Parameters Related to Blood Lead Levels: A Cross-Sectional Biomonitoring Study in an Italian Automotive Plant. [PDF]

Toxics
Tobia L, Mastrantonio R, Muselli M, Nobili G, Cottica D, Cofini V, Necozione S, Fabiani L.   +7 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Childhood Lead Poisoning Prevention Program (CLPPP) 30th anniversary [PDF]

CDC has a long-standing role in childhood lead poisoning prevention. In 2021, CDC\u2019s Childhood Lead Poisoning Prevention Program (CLPPP) commemorates 30 years of funding state and local childhood lead poisoning prevention programs to eliminate ...

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