Results 121 to 130 of about 7,093,189 (263)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Don't spread lead a do-it-yourself guide to lead-safe painting, repair, and home improvement.
, 2006 Title from PDF caption (viewed on July 15, 2008).; "This booklet was developed by the New England Lead Coordinating Committee"--Back cover.; "July 2007.
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Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Lead Poisoning and The Bell Curve [PDF]
A robust environmental health literature demonstrates that preschool lead exposure can cause neurodevelopmental damage and associated adverse impacts on IQ, education, and behavior.
Nevin, Rick
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Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
, 2012 Mohammed Adnan Zolaly1, Manal Ibrahim Hanafi2,3, Nashaat Shawky4, Khalid el-Harbi1, Ahmed M Mohamadin5,61Pediatric Department, 2Family and Community Medicine Department, Medical College, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia ...
Mohamadin AM +4 more
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Introduction Currently, knowledge on relationships between blood concen-trations of cadmium, lead, mercury, selenium, and manganese and the risk of chronic kidney disease (CKD) is lacking.
Shenghua Yao, Dan Xu
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Lead in blood. ICP-MS studies of lead in plasma, blood and erythrocyte proteins
, 1997 An inductively coupled plasma mass spectrometry (ICP-MS) method for the determination of lead in blood plasma has been developed. The detection limit was below 0.1 microgram/liter, and the precision 5%.
Bergdahl, Ingvar A
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