Results 91 to 100 of about 1,226,364 (291)

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Endovascular management of massive post-partum haemorrhage in abnormal placental implantation deliveries [PDF]

, 2015
Objectives: To retrospectively evaluate safety and efficacy of pelvic artery embolisation (PAE) in post-partum haemorrhage (PPH) in abnormal placental implantation (API) deliveries.
Di Renzo, Gian Carlo, Epicoco, Giorgio, Fischer, Matthias, Gerli, Sandro, Graziosi, Luigina, Krokidis, Miltiadis, Maiettini, Daniele, Mosca, Stefano, Orgera, Gianluigi, Rebonato, Alberto, Rossi, Michele, Scialpi, Michele   +11 more
core   +1 more source

Calculation methods for intraoperative blood loss: a literature review

BMC Surgery
Intraoperative bleeding is a common issue in various surgical procedures, and the extent of bleeding significantly impacts the safety, efficacy, and prognosis of surgery. Therefore, accurate assessment of intraoperative blood loss and timely intervention
Yi-Min Lin, Chao Yu, Guo-Zhe Xian
doaj   +1 more source

High-dose tranexamic acid reduces intraoperative and postoperative blood loss in posterior lumbar interbody fusion.

Journal of Neurosurgery : Spine, 2017
OBJECTIVE Tranexamic acid (TXA), a synthetic antifibrinolytic drug, has been reported to reduce blood loss in orthopedic surgery, but there have been few reports of its use in spine surgery. Previous studies included limitations in terms of different TXA
J. Kushioka, Tomoya Yamashita, S. Okuda, T. Maeno, Tomiya Matsumoto, Ryoji Yamasaki, M. Iwasaki   +6 more
semanticscholar   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Circadian Disruption and Metabolic Disease: Findings from Animal Models [PDF]

, 2010
Social opportunities and work demands have caused humans to become increasingly active during the late evening hours, leading to a shift from the predominantly diurnal lifestyle of our ancestors to a more nocturnal one.
Arble, Deanna M., Bass, Joseph, Ramsey, Kathryn Moynihan, Turek, Fred W.   +3 more
core   +2 more sources

Assessment of Outcomes of the Modified Stoppa Approach in the Treatment of Acetabular Fractures: A Retrospective Cohort Study [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy
Aims. To evaluate the efficacy of the modified Stoppa approach for surgical treatment of pelvic bone injuries based on clinical (sex distribution, fracture type), surgical (duration of operation, intraoperative blood loss, incision length, quality of ...
Nurgeldi Manap, Nagmet Mursalov, Mukhtar Abilmazhinov   +2 more
doaj   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Возможности снижения кровопотери при выполнении обширных резекций печени с применением газоструйной диссекции и «малообъемной» инфузионной терапии [PDF]

, 2011
Рішення проблеми крововтрати при великих резекціях печінки є завданням як хірургів, так і анестезіологів. У статті наведені результати застосування методики «малооб’ємної» інфузійної терапії і вдосконаленою хірургічної техніки із застосуванням ...
Гусак, И.В., Козлова, Т.В., Скорый, Д.И.   +2 more
core  

Bariatric surgery and brain health: A longitudinal observational study investigating the effect of surgery on cognitive function and gray matter volume [PDF]

, 2020
Dietary modifications leading to weight loss have been suggested as a means to improve brain health. In morbid obesity, bariatric surgery (BARS)—including different procedures, such as vertical sleeve gastrectomy (VSG), gastric banding (GB), or Roux-en-Y
Flöel, A., Grittner, U., Heßler, S., Ordemann, J., Prehn, K., Profitlich, T., Rangus, I., Witte, A.   +7 more
core   +1 more source