Results 111 to 120 of about 11,357,100 (356)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Effects of Diet Composition and Insulin Resistance Status on Plasma Lipid Levels in a Weight Loss Intervention in Women. [PDF]

open access: yes, 2016
BackgroundOptimal macronutrient distribution of weight loss diets has not been established. The distribution of energy from carbohydrate and fat has been observed to promote differential plasma lipid responses in previous weight loss studies, and insulin
Flatt, Shirley W   +7 more
core   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Four Days in Heaven Spending Four Days in Hell [PDF]

open access: yes, 2012
I spent four days this past weekend wallowing in the depths of hell. Around me swirled the maelstrom of battle, a spinning vortex of blood, death, destruction and loss.
Rudy, John M.
core   +1 more source

Can unilateral, progressive or sudden hearing loss be immune-mediated in origin? [PDF]

open access: yes, 2017
OBJECTIVE: The aim of the present study was to demonstrate that the positivity of nonspecific immunological tests could be found not only in bilateral hearing loss but also in unilateral cases, either sudden or progressive. METHOD: An observational case
Atturo, Francesca   +4 more
core   +1 more source

Estimation of Blood Loss in Total Knee Arthroplasty with or Without Tourniquet

open access: yesPakistan Journal of Medical Research, 2020
Background: Total knee arthroplasty (TKA) is a procedure performed for end stage knee osteoarthritis to reinstate leg function, pain control and improve quality of life. The surgery, however, is associated with a substantial risk of concealed blood loss
Mansoor Ali Khan   +3 more
doaj  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage [PDF]

open access: yes, 2015
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Bate, C, Williams, A
core   +2 more sources

Estimating blood loss during cesarean delivery: A comparison of methods

open access: gold, 2022
Abdulrahim Gari   +6 more
openalex   +1 more source

Home - About - Disclaimer - Privacy