Results 111 to 120 of about 3,348,978 (350)

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

Molecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová, Hana Svozilová, Marcela Krzyžánková, Radim Sonnek, Anastasiya Volakhava, Anastasia Smirnova, Tatiana Grigoreva, Zuzana Jašková, Hana Synáčková, Dennis Wahl, Michaela Bilčíková, Libor Červinek, Šárka Pospíšilová, Ilgar Mamedov, Karla Plevová   +14 more
wiley   +1 more source

The Loss of Fluid and Protein From the Blood During a Systemic Rise of Venous Pressure Produced by Repeated Valsalva Maneuvers in Man1 [PDF]

, 1958
Ellen Brown, James Hopper, John J. Sampson, Charles Mudrick   +3 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Tranexamic acid for reducing blood loss, transfusion requirements, and dosage in pediatric craniosynostosis surgery: a systematic review and meta-analysis

Journal of Pediatric and Neonatal Individualized Medicine
Background: Craniosynostosis surgery is a high risk of substantial blood loss, frequently requiring transfusion. This study evaluates the efficacy of tranexamic acid (TXA) in reducing blood loss and transfusion requirements and examines the administered ...
Alhoi Hendry Henderson, Sabri Ibrahim, Susanty Gazali   +2 more
doaj   +1 more source

ANÆTHESIA AND THE REDUCTION OF BLOOD LOSS [PDF]

, 1952
Will Rollason
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Blood Loss in Paediatric Surgery [PDF]

, 1964
Andrew G. Graham
  +7 more sources

Tranexamic acid versus hot saline irrigations in endoscopic sinus surgery: a review and meta-analysis

Revista Portuguesa Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
Objectives: Intraoperative bleeding may compromise the results of functional endoscopic sinus surgery (FESS). Tranexamic acid (TXA) and hot saline irrigations (HSI) are potentially useful in reducing blood loss during FESS.
Francisco Alves de Sousa, Mariline Santos, Paula Branco, Joana Ida Dias, Sara Costa, Ana Nóbrega Pinto, Luís Meireles, Miguel Gonçalves Ferreira   +7 more
doaj   +1 more source

The Effect of Tranexamic Acid on the Blood Loss Volumes in the Patients Underwent Orthognathic Surgeries [PDF]

Journal of Kerman University of Medical Sciences, 2015
Background and Aims: Tranexamic acid has been used to decrease blood loss volumes and the subsequent need for blood transfusion in the orthopedic, spinal and cardiac surgeries.
Sayed Hossein Mortazavi, Hamid Hamdzadeh, Sara Afsharinia   +2 more
doaj  

CLINICAL STUDIES OF THE BLOOD VOLUME. VIII. MACROCYTIC AND HYPOCHROMIC ANEMIAS DUE TO CHRONIC BLOOD LOSS, HEMOLYSIS AND MISCELLANEOUS CAUSES, AND POLYCYTHEMIA VERA 1 [PDF]

, 1939
John G. Gibson, Alfred W. Harris, Verne W. Swigert   +2 more
openalex   +1 more source