Results 121 to 130 of about 11,219,994 (357)

cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage [PDF]

, 2015
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Bate, C, Williams, A
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Hidden blood loss and its influential factors after total hip arthroplasty

Journal of Orthopaedic Surgery and Research, 2015
BackgroundTotal hip arthroplasty (THA) is a vital therapy for various hip joint diseases. However, patients have lower hemoglobin level post-operatively, remarkably inconsistent with the measured blood loss.
Kaisong Miao, Su Ni, Xianju Zhou, Nanwei Xu, Rongbin Sun, C. Zhuang, Yuji Wang   +6 more
semanticscholar   +1 more source

Influence of patient-related factors on intraoperative blood loss during double opposing Z-plasty Furlow palatoplasty and buccal fat pad coverage: A prospective study

, 2022
Diandra Sabrina Natsir Kalla, Muhammad Ruslin, S. Alkaabi, Andi Sitti Hajrah Yusuf, Andi Tajrin, Tymour Forouzanfar, H. Kuswanto, Paolo Boffano, Lun‐Jou Lo   +8 more
openalex   +1 more source

A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells [PDF]

, 2021
Moeen Riaz, Jonas Mattisson, Galina Polekhina, Andrew Bakshi, Jonatan Halvardson, Marcus Danielsson, Adam Ameur, John J. McNeil, Lars A. Forsberg, Paul Lacaze   +9 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Does the accelerometer-based navigation system reduce blood loss and transfusion in one-stage sequential bilateral total knee arthroplasty? A randomized double-blind controlled trial [PDF]

, 2023
Atthakorn Jarusriwanna, Chaturong Pornrattanamaneewong, Rapeepat Narkbunnam, Pakpoom Ruangsomboon, Paweena Thitithapana, Keerati Chareancholvanich   +5 more
openalex   +1 more source

Rectal Misoprostol in Women Undergoing Myomectomy for Intraoperative Blood Loss Reduction: A double-blinded randomized placebo-controlled study

Thai Journal of Obstetrics and Gynaecology, 2019
Objectives: To compare amount of intraoperative blood loss between patients using preoperative rectal misoprostol versus placebo group.Materials and Methods: A randomized double-blinded placebo-controlled trial, 46 women with uterine leiomyoma indicated
Pruttaporn Maneerat, Sirikarn Tongmai
doaj  

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Four Methods for Calculating Blood-loss after Total Knee Arthroplasty

Chinese Medical Journal, 2015
Background: Currently, various calculation methods for evaluating blood-loss in patients with total knee arthroplasty (TKA) are applied in clinical practice. However, different methods may yield different results.
F. Gao, Zi-jian Li, Ke Zhang, Wei Sun, H. Zhang   +4 more
semanticscholar   +1 more source