Results 51 to 60 of about 1,061,550 (298)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Parameter Inference in the Pulmonary Circulation of Mice [PDF]

, 2017
This study focuses on parameter inference in a pulmonary blood cir- culation model for mice. It utilises a fluid dynamics network model that takes selected parameter values and aims to mimic features of the pulmonary haemody- namics under normal ...
Colebank, Mitchel, Haider, Mansoor A., Hill, Nicholas A., Husmeier, Dirk, Olufsen, Mette S., Paun, L. Mihaela, Qureshi, M. Umar   +6 more
core  

Effect of Thermal Radiation on Biomagnetic Fluid Flow and Heat Transfer over an Unsteady Stretching Sheet

Computer Assisted Methods in Engineering and Science, 2021
This study examines the influence of thermal radiation on biomagnetic fluid, namely blood that passes through a two-dimensional stretching sheet in the presence of magnetic dipole.
Md. Jahangir Alam, Md. Ghulam Murtaza, Efstratios E. Tzirtzilakis, Mohammad Ferdows   +3 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Relating pain intensity of newborns to onset of nonlinear phenomena in cry recordings

, 2005
The cries of several full term newborns, recorded during blood sampling, were analyzed. Spectrograms showed the appearance of irregular patterns related to the pain assessed using the method of the DAN scale.
Angelo Facchini, Barr, Bellieni, Carbajal, Carlo V. Bellieni, Chandre, Elisa B.P. Tiezzi, Facchini, Federico M. Pulselli, Flanagan, Herzel, Herzel, Herzel, Herzel, Hirschberg, Jiang, Lucero, Mende, Michelsson, Nadia Marchettini, Newhouse, Riede, Robb, Steincke, Titze, Tokuda   +25 more
core   +1 more source

Mathematical modeling of local perfusion in large distensible microvascular networks [PDF]

, 2016
Microvessels -blood vessels with diameter less than 200 microns- form large, intricate networks organized into arterioles, capillaries and venules. In these networks, the distribution of flow and pressure drop is a highly interlaced function of single ...
Causin, Paola, Malgaroli, Francesca
core   +2 more sources

Effects of a Complex Feed Additive on Productivity and Blood Parameters of Laying Hens Using Stochastic Fractal-based Neural Network Model [PDF]

Poultry Science Journal
Neural networks (NNs) benefit biomedicine and agriculture, especially when relying on the specificity and implementation of stochastic fractal-supported models.
Larisa Karpenko, Alesya Bakhta, Olga Babich, Stanislav Sukhikh, Nikolay Vorobyov, Ilya Nikonov, Solomonida Borisova, Darren Griffin, Michael Romanov   +8 more
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Model-based computation of total stressed blood volume from a preload reduction manoeuvre [PDF]

, 2015
peer reviewedTotal stressed blood volume is an important parameter for both doctors and engineers. From a medical point of view, it has been associated with the success or failure of fluid therapy, a primary treatment to manage acute circulatory failure.
Chase, J. Geoffrey, Dauby, Pierre, Desaive, Thomas, MORIMONT, Philippe, Pironet, Antoine   +4 more
core   +1 more source

Evaluation of biochemical, histopathological, hematological, and genotoxic effects of some indigenous weed plant extracts in albino rats toward a natural and safe alternative to synthetic insecticides

Frontiers in Veterinary Science
IntroductionThe indiscriminate use of pesticides poses a significant risk to human health and the environment. Plant-based biopesticides offer an alternative to insecticides for integration into insect pest management programs.MethodsThe current study ...
Muhammad Asif Zahoor, Muhammad Kashif Zahoor, Hina Rizvi, Zeeshan Nawaz, Aftab Ahmed, Bushra Munir, Mudassir Hassan, Muhammad Zulhussnain   +7 more
doaj   +1 more source