Results 71 to 80 of about 1,543,423 (268)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Effects of garlic and aspirin on some blood parameters of new zeland rabbits fed cholesterol rich ration [PDF]
Eurasian Journal of Veterinary SciencesIn the study, the effects of aspirin and garlic powder supplementation on some haemotological parameters in hypercholesterolaemic rabbits were investigated.Although the plasma cholesterol level in the groups fed cholesterol -rich ration for 4 weeks ...
Zafer Durgun +3 more
doaj
The Journal of Poultry Science, 2014 This research was conducted to evaluate the effect of organic acid blends (OAB) of ascorbic (A), citric (C), malic (M), sorbic (S), and tartaric (T) acids provided through the drinking water on growth performance, blood constituents, and immune response ...
Ernesto Marín-Flamand +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The haematological influences of seaweed extract on growing japanese quails [PDF]
Eurasian Journal of Veterinary SciencesIn this study we attemted to investigate the effect of seaweed extract (Maxicrop) added at different levels to rations of growing quail chicks. Eighty, one day old Japanese quail chicks were used in this experiment They were randomly distributed in four ...
Ercan Keskin +2 more
doaj
Food and Agricultural Immunology, 2018 Protein undernutrition affects inter alia blood parameters and immune system. These negative effects may be improved by the addition of vitamin B6 to the diet.
Sławomir Lewicki +5 more
doaj +1 more source
The Journal of Poultry Science, 2012 The ban on the use of antibiotics as growth promoters has stimulated the search for alternative feed supplements in poultry production. The active principles of thyme essential oil act as a digestibility enhancer, balancing the gut microbial ecosystem ...
Vahid Khaksar +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source