Results 51 to 60 of about 133,748 (265)

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Comparison and complete mitogenomes of two morphologically similar but ecologically different tick species, Ixodes arboricola and Ixodes lividus (subgenus Pholeoixodes)

Ticks and Tick-Borne Diseases
Ixodes arboricola and Ixodes lividus are ornithophilic tick species. The former is typically associated with tree-hole dwelling birds, while the latter is a host-specific parasite of sand martins (Riparia riparia).
Sándor Hornok, Paulina Lesiczka, Tim Warbroek, Tijs J.M. van den Bosch, Andor Pitó, Gergő Keve, Nóra Takács, Jenő Kontschán, Attila D. Sándor   +8 more
doaj   +1 more source

Injectable Stimuli‐Responsive Amphiphilic Hydrogel for Rapid Hemostasis, Robust Tissue Adhesion, and Controlled Drug Delivery in Trauma and Surgical Care

Advanced Healthcare Materials, EarlyView.
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel, Runali Patil, Abrar Ali Khan, Deeksha Pandit, Kaushik Chatterjee, Maurice N. Collins   +5 more
wiley   +1 more source

An assessment of the possible recent establishment of Hyalomma rufipes in Hungary

Ticks and Tick-Borne Diseases
The aim of this study was to assess the viability of an opportunistic population of Hyalomma rufipes, as evidence of reproduction had been documented in the southern part of Central Europe, specifically Hungary, in 2022.
Gergő Keve, Tekla Varga, Márton Hoitsy, Kata Wermer, Sándor Hornok   +4 more
doaj   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Directional Liquid Transport Enabled pH‐Responsive Hierarchical Composite for Enhanced Wound Healing

Advanced Healthcare Materials, EarlyView.
A hierarchical composite with a gradient architecture transitioning from hydrophobic to hydrophilic layers integrates diode‐like liquid transport, efficient water absorption, breathability, and mechanical robustness. This device enables a multifunctional therapeutic platform with pH‐responsive dual‐drug release, providing synergistic anti‐inflammatory ...
Baolin Wang, Li‐Fang Zhu, Yuna Lang, Siyi Zhang, Fei Chen, Ming‐Wei Chang   +5 more
wiley   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Tick identification and studies of blood parasites in Camels using microscopic and molecular techniques, with special reference to biological control by Metarhizium anisopliae [PDF]

Journal of Bioscience and Applied Research
Recognizing the economic importance of Camelus dromedarius underscores the need for attention to parasitic diseases that threaten their health and productivity, particularly blood parasites and ticks.
Nabawia Elhadidy, Eman Elkelesh, Nahed. Emam, yasmin Mohamed   +3 more
doaj   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Hematological and parasitological health conditions of the Pale-breasted Thrush (Turdus leucomelas) (Passeriformes: Turdidae) in southeastern Brazil

Zoologia (Curitiba), 2011
From an ecological point of view, parasites are considered important selective forces that influence all aspects of a host's life. The purpose of this study was to assess the health state of Turdus leucomelas Vieillot, 1818 (Turdidae: Passeriformes ...
Débora N. C. Lobato, Érika M. Braga, Nayara de O. Belo, Yasmine Antonini   +3 more
doaj   +1 more source