Results 1 to 10 of about 14,390 (182)
The Biogeography of Apicomplexan Parasites in Tropical Soils [PDF]
Ecology and EvolutionParasitic protists such as Apicomplexa, an abundant group of soil protists, contribute to ecosystem processes and nutrient cycling in belowground soil systems through their obligate symbioses with soil Metazoa.
Rachel M. Shepherd, Angela M. Oliverio
doaj +2 more sources
The flexibility of Apicomplexa parasites in lipid metabolism
PLoS Pathogens, 2022 Apicomplexa are obligate intracellular parasites responsible for major human infectious diseases such as toxoplasmosis and malaria, which pose social and economic burdens around the world.
Serena Shunmugam +4 more
doaj +5 more sources
Essential Genes of the Parasitic Apicomplexa [PDF]
Trends in Parasitology, 2021 Genome-scale mutagenesis screens for genes essential for apicomplexan parasite survival have been completed in three species: Plasmodium falciparum, the major human malaria parasite, Plasmodium berghei, a model rodent malaria parasite, and the more distantly related Toxoplasma gondii, the causative agent of toxoplasmosis. These three species share 2606
Oberstaller, Jenna +3 more
openaire +2 more sources
mSphere, 2022 Chromatin dynamics can regulate all DNA-dependent processes. Access to DNA within chromatin is orchestrated mainly by histones and their posttranslational modifications (PTMs).
Vanessa Severo +6 more
doaj +1 more source
The Actomyosin Systems in Apicomplexa [PDF]
, 2020 The phylum of Apicomplexa groups obligate intracellular parasites that exhibit unique classes of unconventional myosin motors. These parasites also encode a limited repertoire of actins, actin-like proteins, actin-binding proteins and nucleators of filamentous actin (F-actin) that display atypical properties.
Frenal, Karine +2 more
openaire +3 more sources
mSphere, 2021 Currently, the drugs used for toxoplasmosis have severe toxicity to human cells, and the treatment still lacks effective and safer alternatives. The search for novel drug targets is timely.
Mariana Galvão Ferrarini +12 more
doaj +1 more source
Extrachromosomal DNA in the Apicomplexa. [PDF]
Microbiology and molecular biology reviews : MMBR, 1997 Malaria and related apicomplexan parasites have two highly conserved organellar genomes: one is of plastid (pl) origin, and the other is mitochondrial (mt). The organization of both organellar DNA molecules from the human malaria parasite Plasmodium falciparum has been determined, and they have been shown to be tightly packed with genes.
R J, Wilson, D H, Williamson
openaire +3 more sources
Crystals, 2022 A model for parasitic motility has been proposed in which parasite filamentous actin (F-actin) is attached to surface adhesins by a large component of the glideosome, known as the glideosome-associated connector protein (GAC).
Amit Kumar +8 more
doaj +1 more source
Identification and Validation of Toxoplasma gondii Mitoribosomal Large Subunit Components
Microorganisms, 2022 Mitochondrial ribosomes are fundamental to mitochondrial function, and thus survival, of nearly all eukaryotes. Despite their common ancestry, mitoribosomes have evolved divergent features in different eukaryotic lineages.
Shikha Shikha +2 more
doaj +1 more source
Mobilome of Apicomplexa Parasites
Genes, 2022 Transposable elements (TEs) are mobile genetic elements found in the majority of eukaryotic genomes. Genomic studies of protozoan parasites from the phylum Apicomplexa have only reported a handful of TEs in some species and a complete absence in others.
Matias Rodriguez, Wojciech Makalowski
openaire +3 more sources