Results 101 to 110 of about 7,072,300 (361)
FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Разработка и регистрация лекарственных средствIntroduction. Etmaben is a promising drug for the treatment of cardiovascular diseases, widely studied in preclinical studies. In order to conduct phase I clinical trials, it is necessary to develop a bioanalytical method for the quantitative ...
P. K. Karnakova +7 more
doaj +1 more source
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
FEBS Open Bio, EarlyView.Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
Разработка и регистрация лекарственных средствIntroduction. The number of peptide drugs being developed and registered has increased in recent years. Therefore, modern analytical approaches and methods are required to determine these substances in biological matrices during pharmacokinetic studies ...
M. A. Tokareva +5 more
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THE DETERMINATION OF ALBUMIN IN HUMAN BLOOD PLASMA AND SERUM. A METHOD BASED ON THE INTERACTION OF ALBUMIN WITH AN ANIONIC DYE—2-(4′-HYDROXYBENZENEAZO) BENZOIC ACID 12 [PDF]
, 1954 David D. Rutstein +3 more
openalex +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
FEBS Open Bio, EarlyView.The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
Опухоли женской репродуктивной системы, 2014 At present, there is no screening test for the early detecting and monitoring of ovarian cancer, one of the most lethal form of gynaecological malig- nancy in the worldwide.
V. E. Shevchenko +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo +11 more
wiley +1 more source
Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro +12 more
wiley +1 more source
VALIDAÇÃO DE MÉTODO POR MEFS-HS/CG-EM PARA DETERMINAÇÃO DE CARBARIL EM PLASMA SANGUÍNEO
Química NovaThe aim this research is to develop a HS-SPME/GC-MS method to analyze the carbaryl in blood plasma samples of the rural workers, who live round the perimeter of Chapada do Apodi-CE. This was achieved by chromatographic signal of the 1-naftol, degradation
Francisco Thiago C. de Souza +6 more
doaj +1 more source