Results 11 to 20 of about 4,927,683 (288)

Analysis of imatinib in bone marrow and plasma samples of chronic myeloid leukaemia patients using solid phase extraction LC-ESI-MS [PDF]

, 2011
The LC-ESI-MS was developed and validated for the analysis of imatinib in plasma and bone marrow samples using deuterated imatinib (D(8)-IM) as an internal standard. The biological samples were extracted using Strata-X-C SPE cartridges and separated on C&
Holyoake, T.L., Iqbal, Zafar, Jorgensen, H.G., Watson, David, Holyoake, Tessa, Elliott, M., Elliott, Moira, Iqbal, Z., Jørgensen, Heather, Watson, D.G.   +9 more
core   +11 more sources

Application of FTIR to detect changes in blood plasma during a pre-competition period in a professional heavyweight boxer [PDF]

Frontiers in Physiology
Objectives and designThis exploratory single-case study examined whether repeated attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy of blood plasma is technically feasible during a short pre-competition period and whether ...
Paweł Król, Joanna Depciuch, Joanna Depciuch, Adam Reich, Józef Cebulski, Zbigniew Obmiński, Krzysztof Kasicki, Wojciech Czarny, Wojciech Czarny, Łukasz Różański, Łukasz Rydzik   +10 more
doaj   +2 more sources

Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study [PDF]

, 2000
The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an ...
Packard, C., James Shepherd, Cobbe, S., John Norrie, Macfarlane, P., Lowe, G., Ian Ford, Ford, I., Rumley, A., Ann Rumley, null null, Peter Macfarlane, Stuart Cobbe, Christopher Packard, Norrie, J., Gordon Lowe, Shepherd, J.   +16 more
core   +7 more sources

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S., Day, SP, Caslake, MJ, Chaudhry, MA, Chaudhry, M.A., Muriithi, E.W., Wheatley, DJ, Muriithi, EW, Belcher, P.R., Belcher, PR   +9 more
core   +6 more sources

Micro-scale blood plasma separation: from acoustophoresis to egg-beaters [PDF]

, 2013
Plasma is a rich mine of various biomarkers including proteins, metabolites and circulating nucleic acids. The diagnostic and therapeutic potential of these analytes has been quite recently uncovered, and the number of plasma biomarkers will still be ...
Sollier, Elodie, Kersaudy-Kerhoas, Maïwenn; id_orcid   +1 more
core   +1 more source

Cellular expression of plasma prekallikrein in human tissues [PDF]

, 2007
Plasma prekallikrein (PPK) is synthesised in hepatocytes and secreted into the blood, where it participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation.
Celia Snyman, Chirurgische Klinik Innenstadt, Figueroa, Carlos D., Neth, Peter, Bhoola, Kanti D., Snyman, Celia, Edwin Fink, Carlos D. Figueroa, Peter Neth, Fink, Edwin, Kanti D. Bhoola   +10 more
core   +1 more source

von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII

Haematologica, 2016
It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derived ...
Nicoletta Sorvillo, Robin B. Hartholt, Esther Bloem, Magdalena Sedek, Anja ten Brinke, Carmen van der Zwaan, Floris P. van Alphen, Alexander B. Meijer, Jan Voorberg   +8 more
doaj   +1 more source

Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors–In Vitro and In Silico Studies

Molecules, 2021
The Pulmonaria species (lungwort) are edible plants and traditional remedies for different disorders of the respiratory system. Our work covers a comparative study on biological actions in human blood plasma and cyclooxygenase-2 (COX-2) -inhibitory ...
Justyna Krzyżanowska-Kowalczyk, Mariusz Kowalczyk, Michał B. Ponczek, Łukasz Pecio, Paweł Nowak, Joanna Kolodziejczyk-Czepas   +5 more
doaj   +1 more source

A Nuclear Magnetic Resonance Spectroscopy Method in Characterization of Blood Metabolomics for Alzheimer’s Disease

Metabolites, 2022
There is currently a crucial need for improved diagnostic techniques and targeted treatment methods for Alzheimer’s disease (AD), a disease which impacts millions of elderly individuals each year.
JianXiang Weng, Isabella H. Muti, Anya B. Zhong, Pia Kivisäkk, Bradley T. Hyman, Steven E. Arnold, Leo L. Cheng   +6 more
doaj   +1 more source

Metabolic Signatures of Lung Cancer in Biofluids: NMR-Based Metabonomics of Blood Plasma [PDF]

, 2011
In this work, the variations in the metabolic profile of blood plasma from lung cancer patients and healthy controls were investigated through NMR-based metabonomics, to assess the potential of this approach for lung cancer screening and diagnosis.
Joana Carrola, Brian J. Goodfellow, Carreira, Isabel M., Goodfellow, Brian J., Rocha, Cláudia M., Gil, Ana M., Carvalho, Lina, Cláudia M. Rocha, António S. Barros, Lina Carvalho, Barros, António S., Ana Gomes, Bernardo, Joao, Carrola, Joana, Sousa, Vitor, Ana M. Gil, João Bernardo, Vitor Sousa, Gomes, Ana, Iola F. Duarte, Isabel M. Carreira, Duarte, Iola F.   +21 more
core   +1 more source