Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) [PDF]
, 2011 <p>Background: Venous thromboembolic events (VTE), including deep venous thrombosis and pulmonary embolism, are common in older age. It has been suggested that statins might reduce the risk of VTE however positive results from studies of middle ...
A Gaw +43 more
core +4 more sources
Coarse-grained model of adsorption of blood plasma proteins onto nanoparticles. [PDF]
Journal of Chemical Physics, 2015 We present a coarse-grained model for evaluation of interactions of globular proteins with nanoparticles (NPs). The protein molecules are represented by one bead per aminoacid and the nanoparticle by a homogeneous sphere that interacts with the ...
Hender Lopez, V. Lobaskin
semanticscholar +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Exposure to Endocrine Disruptors and Nuclear Receptors Gene Expression in Infertile and Fertile Men from Italian Areas with Different Environmental Features [PDF]
, 2015 Internal levels of selected endocrine disruptors (EDs) (i.e., perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), di-2-ethylhexyl-phthalate (DEHP), mono-(2-ethylhexyl)-phthalate (MEHP), and bisphenol A (BPA)) were analyzed in blood/serum of ...
Bergamasco B +14 more
core +2 more sources
Asparagine in Blood Plasma [PDF]
Nature, 1953 FREE asparagine has twice before been reported in animal tissues, namely, in the liver, kidney and spleen of sheep1, and, recently, in human urine2. The evidence given below shows that it is also present in the blood plasma of both man and the goat: the concentrations are, in fact, comparable to those of many other free amino-acids in blood plasma.
openaire +2 more sources
Mechanism of Copper Uptake from Blood Plasma Ceruloplasmin by Mammalian Cells
PLoS ONE, 2016 Ceruloplasmin, the main copper binding protein in blood plasma, has been of particular interest for its role in efflux of iron from cells, but has additional functions.
Danny Ramos +6 more
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Optimizing Measurement of Vascular Endothelial Growth Factor in Small Blood Samples of Premature Infants [PDF]
, 2019 To establish a method that allows for the reliable assessment of vascular endothelial growth factor (VEGF-A) concentrations in very small blood samples of preterm infants. Systemic VEGF measurements are important in view of the most appropriate Anti-VEGF
Lopez Yomayuza, Claudia C. +3 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Proteins involved in the Vroman effect during exposure of human blood plasma to glass and polyethylene [PDF]
, 1996 The amounts of fibrinogen adsorbed to glass from various human blood plasmas have been measured as a function of time. The plasmas were 11 single donor plasmas, pooled plasma, a single donor high molecular weight kininogen (HMWK)-deficient plasma and ...
Beugeling, T., Poot, A.A., Turbill, P.
core +3 more sources