Results 41 to 50 of about 7,072,300 (361)

Coarse-grained model of adsorption of blood plasma proteins onto nanoparticles. [PDF]

open access: yesJournal of Chemical Physics, 2015
We present a coarse-grained model for evaluation of interactions of globular proteins with nanoparticles (NPs). The protein molecules are represented by one bead per aminoacid and the nanoparticle by a homogeneous sphere that interacts with the ...
Hender Lopez, V. Lobaskin
semanticscholar   +1 more source

Chimeric antigen receptor T-cells: a review on current status and future directions for relapsed/refractory multiple myeloma

open access: yesFrontiers in Oncology
Although multiple myeloma is an incurable disease, the past decade has witnessed significant improvement in patient outcomes. This was brought about by the development of T-cell redirection therapies such as chimeric antigen receptor (CAR) T-cells, which
Issam S. Hamadeh   +3 more
doaj   +1 more source

Simple, selective, and sensitive measurement of urea in body fluids of mammals by reversed-phase ultra-fast liquid chromatography

open access: yesCzech Journal of Animal Science, 2012
Ultra-fast liquid chromatography with a photodiode array detector for simple and rapid determination of urea in body fluids of farm animals is described.
M. Czauderna, J. Kowalczyk
doaj   +1 more source

Mechanism of Copper Uptake from Blood Plasma Ceruloplasmin by Mammalian Cells

open access: yesPLoS ONE, 2016
Ceruloplasmin, the main copper binding protein in blood plasma, has been of particular interest for its role in efflux of iron from cells, but has additional functions.
Danny Ramos   +6 more
semanticscholar   +1 more source

Viscosity of Plasma as a Key Factor in Assessment of Extracellular Vesicles by Light Scattering

open access: yesCells, 2019
Extracellular vesicles (EVs) isolated from biological samples are a promising material for use in medicine and technology. However, the assessment methods that would yield repeatable concentrations, sizes and compositions of the harvested material are ...
Darja Božič   +7 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Capillary flow-driven microfluidic device with wettability gradient and sedimentation effects for blood plasma separation

open access: yesScientific Reports, 2017
We report a capillary flow-driven microfluidic device for blood-plasma separation that comprises a cylindrical well between a pair of bottom and top channels.
M. Maria, P. Rakesh, T. Chandra, A. Sen
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

The Role of Neuropeptide Y in the Pathogenesis of Alzheimer’s Disease: Diagnostic Significance and Neuroprotective Functions

open access: yesNeurology International
Background. Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases. It has been suggested that the factors that cause pathologic changes and lead to the development of AD may also include changes in certain neuropeptides.
Ksenia Shapovalova   +5 more
doaj   +1 more source

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