Results 271 to 280 of about 283,642 (353)
Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis
Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm +2 more
wiley +1 more source
Automated Imaging and Analysis of Platelet, Coagulation and Fibrinolysis Activities Using a Novel Flow Chip-Based System at Physiological Temperature. [PDF]
Gui X +4 more
europepmc +1 more source
[Production and breakdown of blood platelets in various platelet disorders].
openaire +1 more source
Objective The therapeutic effects of telitacicept combined with standard of care (SoC) in childhood‐onset systemic lupus erythematosus (cSLE) remain unclear. This study aims to evaluate its efficacy in comparison with belimumab combined with SoC.
Chong Luo +15 more
wiley +1 more source
[Diagnostic tests of blood platelets in patients with platelet disorders].
openaire +1 more source
Prothrombotic Activation of Platelet Pannexin‐1 Channels in Antiphospholipid Syndrome
Objective ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. The objective of this study was to evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired ...
Bruna de Moraes Mazetto Fonseca +13 more
wiley +1 more source
Characterization of Novel Variants in <i>P2YRY12, GP6</i> and <i>TBXAS1</i> in Patients with Lifelong History of Bleeding. [PDF]
Zamora-Cánovas A +12 more
europepmc +1 more source
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati +13 more
wiley +1 more source

