Results 311 to 320 of about 629,937 (377)

Studies on human blood platelets in affective disorder

Psychopharmacology, 1979
Platelets were examined to enable a simultaneous investigation to be made of indolylamine and electrolyte metabolism in affective disorder. No significant differences were detected in either platelet membrane ATPase or adenyl cyclase specific activity in any of the groups of patients studied, when compared with appropriate controls.
H. W. Reading   +2 more
openaire   +3 more sources

The Enumeration of the Blood-Platelets in Mental Disorders [PDF]

open access: possibleJournal of Mental Science, 1937
On looking through the literature relating to the blood-picture in various types of mental disorders, one finds that most workers have confined themselves to the red and white cells only. Relatively little attention has been given to the study of the third element of the blood, namely, the blood-platelet.
openaire   +1 more source

Platelet Aggregation in Platelet-Rich Plasma and Whole Blood in 120 Patients with Myeloproliferative Disorders

American Journal of Clinical Pathology, 1991
In vitro platelet aggregation in platelet-rich plasma (PRP) and in whole blood (WB) was assessed in 31 patients with idiopathic myelofibrosis, 32 with essential thrombocytosis, 23 with polycythemia vera, and 34 with chronic myelogenous leukemia. In PRP most subjects showed normal or reduced platelet aggregation, whereas in WB the majority of patients ...
BALDUINI, CARLO   +3 more
openaire   +3 more sources

Familial Bleeding Disorder with a Moderate Thrombocytopenia and Giant Blood Platelets

Scandinavian Journal of Haematology, 1974
Among 10 siblings in an otherwise healthy family two sisters had experienced serious bleeding tendency from early childhood. They were moderately thrombocytopenic, their primary bleeding time was prolonged, and splenectomy had been performed in both without effect. One of them, now aged 66, was admitted because of recurrent episodes of life‐threatening
Mll A. Grøttum   +3 more
openaire   +3 more sources

Paroxetine binding in the blood platelets of post-traumatic stress disorder patients

Life Sciences, 1993
Platelet serotonin (5-HT) uptake, as determined by 3H-paroxetine (PA) binding, was studied in 20 Post-traumatic Stress Disorder (PTSD) patients and 20 normal controls. Kd (an inverse measure of affinity of 3H-PA binding to uptake sites) and Bmax (maximum number of 3H-PA binding sites) of 3H-PA binding were significantly decreased in PTSD patients as ...
Ramesh C. Arora   +5 more
openaire   +3 more sources

Mitochondrial Dysfunction in Blood Platelets of Patients with Manic Episode of Bipolar Disorder

CNS & Neurological Disorders - Drug Targets, 2019
Objectives: The bipolar affective disorder (BAD) pathophysiology is multifactorial and has not been fully clarified. Method: We measured selected mitochondrial parameters in peripheral blood components. The analyses were performed for patients suffering from a manic episode during remission and were compared to those performed for healthy controls ...
Jana Hroudová   +7 more
openaire   +3 more sources

Inherited platelet disorders and oral health.

Journal of Oral Pathology & Medicine, 2013
Platelets play a key role in thrombosis and hemostasis. Accumulation of platelets at the site of vascular injury is the first step in the formation of hemostatic plugs, which play a pivotal role in preventing blood loss after injury. Platelet adhesion at
Marie-Cécile Valéra   +4 more
semanticscholar   +1 more source

Molecular Disorders of Red Blood Cells, Platelets, and Coagulation System

2017
This chapter comprehensively describes not only the molecular origin of disorders of red blood cells, coagulation factors, fibrinolytic proteins, and platelets but also the clinical manifestations, diagnostic procedures, therapeutic approaches, and management of affected patients.
Allen W. Root, Jennifer L.R. Mayer
openaire   +2 more sources

Serotonin uptake and imipramine binding in the blood platelets of obsessive-compulsive disorder patients

Biological Psychiatry, 1991
14C-Serotonin (5-HT) uptake and 3H-imipramine binding (IB) were studied in the blood platelets of 20 obsessive-compulsive disorder (OCD) patients, 53 normal controls (5-HT uptake) and 32 normal controls (IB binding). The maximum number of binding sites (Bmax) was significantly decreased in OCD patients compared to normal controls, but there was no ...
Herbert Y. Meltzer   +2 more
openaire   +3 more sources

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