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Effect of lithium carbonate on serotonin uptake in blood platelets of patients with affective disorders

Journal of Affective Disorders, 1983
Lithium carbonate treatment for 2-3 weeks produced a significant decrease in the maximum velocity (Vmax) of serotonin (5-HT) uptake, a measure of the number of 5-HT uptake sites in blood platelets from bipolar patients. The decrease was more pronounced in bipolar manic patients than bipolar depressed patients.
Herbert Y. Meltzer   +2 more
openaire   +3 more sources

Blood Platelet as a Peripheral Cell in Oxidative Stress in Psychiatric Disorders

2014
Enhanced production of reactive oxygen/nitrogen species (ROS/RNS) and the oxidative changes in the brain may be reflected by abnormalities in peripheral blood platelets from patients with psychiatric diseases. Platelets, the smallest anucleated blood cells with a relatively short half-life time, are useful models to study the mechanism of cell ...
openaire   +2 more sources

Platelet 5‐Hydroxytryptamine (HT) in Disorders of the Blood

British Journal of Haematology, 1957
R. S. Stacey, R. M. Hardisty
openaire   +3 more sources

Investigation of platelet function and platelet disorders using flow cytometry

Platelets, 2016
P. Rubak   +3 more
semanticscholar   +1 more source

Blood platelet and "extra-platelet" serotonin in some myeloproliferative disorders.

Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1978
Most of the blood serotonin is bound to platelets. However, some authors described plasma "free" serotonin; which is normally very low, and might be increased during some diseases. Usual spectrofluorimetric methods and paired by statistical evaluation "extra-platelet" serotonin (not bound to platelets) in the blood of healthy volunteers and patients ...
J M, Culebras Poza   +3 more
openaire   +1 more source

Platelet disorders: an overview

Blood Coagulation and Fibrinolysis, 2015
M. Krishnegowda, V. Rajashekaraiah
semanticscholar   +1 more source

Platelet and Blood Vessel Disorders

2011
J. Paul Scott, Robert R. Montgomery
openaire   +1 more source

CLINICAL DISORDERS RELATED TO BLOOD PLATELETS

1971
Charles A. Owen, E.J.Walter Bowie
openaire   +2 more sources

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