Results 81 to 90 of about 629,937 (377)
Background. Arterial hypertension during pregnancy is accompanied by pronounced changes in microcirculation and hemostasis in the system, the state of which is largely determined by the structural and functional properties of red blood cells and ...
R. I. Sadov+4 more
doaj +1 more source
A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams+158 more
core +1 more source
Bioprinted Micro‐Clots for Kinetic Analysis of Endothelial Cell‐Mediated Fibrinolysis
This paper describes the development of a microscale model that quantifies the breakdown of fibrin by endothelial cells. The small size scale of this engineered system enables fibrin breakdown to be observed without the addition of external activators. This system could help in identifying compounds which both promote and hinder thrombosis.
Jonathan J. Chang+5 more
wiley +1 more source
Current Knowledge on Inherited Platelet Function Disorders
Inherited platelet function disorders (IPFDs) are rare and underdiagnosed in individuals with clinically significant bleeding diathesis. IPFDs are classified according to the causative molecular defects involved in the process of primary hemostasis of ...
Nani Jung, Ye Jee Shim
doaj +1 more source
Seasonal variation of platelets in a cohort of Italian blood donors: a preliminary report [PDF]
Massimo Gallerani1*, Roberto Reverberi2, Raffaella Salmi1, Michael H Smolensky3 and Roberto Manfredini4 Author Affiliations 1 Internal Medicine, Azienda Ospedaliera-Universitaria, Ferrara, Italy 2 Immunohematological and Transfusional Service, Azienda ...
Gallerani, Massimo+4 more
core +2 more sources
Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee+10 more
wiley +1 more source
Advances in Platelet-Dysfunction Diagnostic Technologies
The crucial role of platelets in hemostasis and their broad implications under various physiological conditions underscore the importance of accurate platelet-function testing. Platelets are key to clotting blood and healing wounds.
Inkwon Yoon+2 more
doaj +1 more source
Device-Induced Hemostatic Disorders in Mechanically Assisted Circulation
Mechanically assisted circulation (MAC) sustains the blood circulation in the body of a patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) or on ventricular assistance with a ventricular assist device (VAD) or on extracorporeal ...
Shigang Wang MD+2 more
doaj +1 more source
Garlic inhibitory effect on platelet activity induced by different agonists
Platelets are essential elements of human blood. In addition to their normal role, platelets are involved in causing myocardial infarction, stroke and other thrombotic disorders.
Roxana Elizabeth González+3 more
doaj +1 more source
Vascular diseases such as myocardial infarction and ischemic stroke are associated with increased platelet function whilst the risk of recurrence is reduced by antiplatelet agents such as aspirin, clopidogrel, and prasugrel.
P. Bath, J. May, S. Heptinstall
semanticscholar +1 more source