Results 131 to 140 of about 5,011,779 (389)
ABSTRACT Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition. Methods Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment ...
Jade Hannan+8 more
wiley +1 more source
Techniques for combined procurement of hearts and kidneys with satisfactory early function of renal allografts. [PDF]
Methods for combination of donor nephrectomy with donor cardiectomy are outlined. The satisfactory early function of 29 of 34 transplanted kidneys harvested with these techniques supports their wider application and should encourage their wider ...
Bahnson, HT+7 more
core
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun+8 more
wiley +1 more source
Effect of MAP on preservation quality of deglycerolized red blood cells
Objective To observe the effect of deglycerolized red blood cells suspended in MAP on preservation and explore the most effective preservation method. Methods Concentrated red blood cells were prepared by centrifuging 400 mL of whole blood on the third ...
Jianhao YANG+7 more
doaj +1 more source
A New Approach for Evaluating and Improving the Performance of Segmentation Algorithms on Hard-to-Detect Blood Vessels [PDF]
Many studies regarding the vasculature of biological tissues involve the segmentation of the blood vessels in a sample followed by the creation of a graph structure to model the vasculature. The graph is then used to extract relevant vascular properties.
arxiv
Modeling Biological Membrane and Red Blood Cells by Coarse- Grained Particle Method [PDF]
In this work, we review previously developed coarse-grained (CG) particle models for biological membrane and red blood cells (RBCs) and discuss the advantages of the CG particle method over the continuum and atomic simulations on modeling biological phenomena. CG particle models can largely increase the length scale and time scale of atomic simulations
arxiv
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
THE PRESERVATION OF WHOLE BLOOD 1 [PDF]
Miss Margaret Dolan+5 more
openaire +3 more sources
Learning compressed representations of blood samples time series with missing data [PDF]
Clinical measurements collected over time are naturally represented as multivariate time series (MTS), which often contain missing data. An autoencoder can learn low dimensional vectorial representations of MTS that preserve important data characteristics, but cannot deal explicitly with missing data.
arxiv
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source