Results 81 to 90 of about 10,112,832 (405)

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Association of Blood Pressure Lowering With Mortality and Cardiovascular Disease Across Blood Pressure Levels: A Systematic Review and Meta-analysis

JAMA Internal Medicine, 2018
Importance High blood pressure (BP) is the most important risk factor for death and cardiovascular disease (CVD) worldwide. The optimal cutoff for treatment of high BP is debated.
M. Brunström, B. Carlberg
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Relationship between blood pressure and flow rate in arteries using a modified Windkessel model [PDF]

arXiv, 2020
This study examined the flow rate in arteries using the modified Windkessel model, considering various models for blood pressure. An exact solution was derived using a Laplace transform method and the effects of blood pressure on the flow rate in an artery were examined.
arxiv  

Raja Bandung Banana (Musa ParadisiacaL.cv Raja Bandung) Prevents Increased Systolic Blood Pressure in Rats Given Acute Stress Test [PDF]

, 2015
The relationships between stress and hypertension have been evaluated. Heightened blood pressure (BP) reactions to acute stress have been implicated in cardiovascular disease\u27s development. Consumption of fruit or vegetables lowering BP.
Anindyah, D. S. (Dina), Farmawati, A. (Arta)   +1 more
core   +2 more sources

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

Science, 2018
Heart rate and blood pressure control PIEZO1 and PIEZO2 are two mechanically activated ion channels that are highly expressed in lungs, bladder, and skin. Zeng et al.
W. Zeng, Kara L. Marshall, Soohong Min, I. Daou, M. Chapleau, F. Abboud, S. Liberles, A. Patapoutian   +7 more
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Developing Personalized Models of Blood Pressure Estimation from Wearable Sensors Data Using Minimally-trained Domain Adversarial Neural Networks [PDF]

arXiv, 2020
Blood pressure monitoring is an essential component of hypertension management and in the prediction of associated comorbidities. Blood pressure is a dynamic vital sign with frequent changes throughout a given day. Capturing blood pressure remotely and frequently (also known as ambulatory blood pressure monitoring) has traditionally been achieved by ...
arxiv  

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Nature Genetics, 2018
In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis.
Ayush Giri, J. Hellwege, Jacob M. Keaton, Jihwan Park, Chengxiang Qiu, H. Warren, E. Torstenson, C. Kovesdy, Yan V. Sun, O. Wilson, C. Robinson-Cohen, C. Roumie, C. Chung, K. Birdwell, S. Damrauer, S. Duvall, D. Klarin, Kelly Cho, Yu Wang, E. Evangelou, C. Cabrera, L. Wain, Rojesh Shrestha, Brian S. Mautz, Elvis Akwo, M. Sargurupremraj, S. Debette, M. Boehnke, L. Scott, J. Luan, Jinghua Zhao, Sara M. Willems, S. Thériault, Nabi Shah, C. Oldmeadow, P. Almgren, R. Li-Gao, N. Verweij, Thibaud S. Boutin, M. Mangino, I. Ntalla, E. Feofanova, P. Surendran, J. Cook, Savita Karthikeyan, N. Lahrouchi, Chunyu Liu, N. Sepúlveda, T. Richardson, A. Kraja, P. Amouyel, M. Farrall, N. Poulter, M. Laakso, E. Zeggini, P. Sever, R. Scott, C. Langenberg, N. Wareham, D. Conen, C. Palmer, J. Attia, D. Chasman, P. Ridker, O. Melander, D. Mook-Kanamori, P. Harst, F. Cucca, D. Schlessinger, C. Hayward, T. Spector, M. Jarvelin, B. Hennig, N. Timpson, Wei-Qi Wei, Joshua C. Smith, Yaomin Xu, M. Matheny, E. Siew, C. Lindgren, K. Herzig, G. Dedoussis, J. Denny, B. Psaty, J. Howson, P. Munroe, C. Newton‐Cheh, M. Caulfield, P. Elliott, J. Gaziano, J. Concato, P. Wilson, P. Tsao, D. V. Velez Edwards, K. Suszták, C. O’Donnell, A. Hung, T. Edwards, Understanding Society Scientific Group, International Consortium for Blood Pressure, Blood Pressure-International Consortium of Exome Chip Studies, Million Veteran Program   +101 more
semanticscholar   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source