Results 81 to 90 of about 8,910,389 (314)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Nature Genetics, 2016 To dissect the genetic architecture of blood pressure and assess effects on target organ damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 individuals of European ancestry, and genotypes from an additional 140,886 ...George B. Ehret, T. Ferreira, D. Chasman, A. Jackson, Ellen M. Schmidt, T. Johnson, G. Thorleifsson, J. Luan, L. Donnelly, S. Kanoni, A. Petersen, Vasyl Pihur, R. Strawbridge, D. Shungin, Maria F Hughes, Osorio Meirelles, M. Kaakinen, N. Bouatia-Naji, K. Kristiansson, Sonia H. Shah, M. Kleber, Xiuqing Guo, L. Lyytikäinen, Cristiano Fava, N. Eriksson, I. Nolte, Patrik K. E. Magnusson, Elias L Salfati, L. Rallidis, E. Theusch, Andrew J P Smith, L. Folkersen, K. Witkowska, T. Pers, R. Joehanes, Stuart K. Kim, Lazaros Lataniotis, R. Jansen, Andrew D. Johnson, H. Warren, Young Jin Kim, Wei Zhao, Ying Wu, B. Tayo, M. Bochud, D. Absher, Linda S. Adair, N. Amin, D. Arking, T. Axelsson, D. Baldassarre, B. Balkau, S. Bandinelli, Michael R Barnes, Inês Barroso, S. Bevan, J. Bis, G. Bjornsdottir, M. Boehnke, E. Boerwinkle, L. Bonnycastle, D. Boomsma, Stefan R Bornstein, Morris J. Brown, M. Burnier, Claudia P. Cabrera, J. Chambers, I. Chang, Ching-Yu Cheng, P. Chines, R. Chung, F. Collins, J. Connell, A. Döring, J. Dallongeville, J. Danesh, U. de Faire, G. Delgado, A. Dominiczak, A. Doney, F. Drenos, S. Edkins, J. Eicher, R. Elosúa, Stefan Enroth, J. Erdmann, P. Eriksson, T. Esko, E. Evangelou, A. Evans, T. Fall, M. Farrall, J. Felix, J. Ferrières, L. Ferrucci, M. Fornage, T. Forrester, N. Franceschini, Oscar H. Franco, A. Franco-Cereceda, Ross M. Fraser, S. Ganesh, He Gao, K. Gertow, F. Gianfagna, B. Gigante, Franco Giulianini, A. Goel, A. H. Goodall, M. Goodarzi, Mathias Gorski, J. Grässler, C. Groves, V. Gudnason, U. Gyllensten, G. Hallmans, A. Hartikainen, M. Hassinen, A. Havulinna, C. Hayward, S. Hercberg, K. Herzig, A. Hicks, A. Hingorani, J. Hirschhorn, A. Hofman, J. Holmen, O. Holmen, J. Hottenga, Philip J Howard, C. Hsiung, Steven C. Hunt, M. A. Ikram, T. Illig, C. Iribarren, Rich Jensen, M. Kähönen, Hyun Min Kang, S. Kathiresan, Brendan J. Keating, K. Khaw, Y. Kim, Eric Kim, M. Kivimaki, N. Klopp, G. Kolovou, P. Komulainen, J. Kooner, Gülüm Kosova, Ronald M. Krauss, D. Kuh, Z. Kutalik, J. Kuusisto, K. Kvaløy, T. Lakka, N. Lee, I-T Lee, Wen-Jane Lee, D. Levy, Xiaohui Li, Kae-Woei Liang, Honghuang Lin, L. Lin, J. Lindström, S. Lobbens, S. Männistö, G. Müller, M. Müller-Nurasyid, F. Mach, Hugh S. Markus, E. Marouli, M. McCarthy, C. McKenzie, P. Meneton, C. Menni, A. Metspalu, Vladan Mijatovic, L. Moilanen, M. Montasser, Andrew D. Morris, A. Morrison, A. Mulas, R. Nagaraja, Narisu Narisu, K. Nikus, Christopher J. O'Donnell, Paul F. O’Reilly, Ken K Ong, F. Paccaud, Cameron D. Palmer, A. Parsa, Nancy L Pedersen, B. Penninx, M. Perola, A. Peters, N. Poulter, P. Pramstaller, B. Psaty, T. Quertermous, D. Rao, A. Rasheed, N. Rayner, F. Renström, R. Rettig, Kenneth M. Rice, R. Roberts, L. Rose, J. Rossouw, Nilesh J. Samani, S. Sanna, J. Saramies, H. Schunkert, S. Sebert, W. H. Sheu, Young-Ah Shin, Xueling Sim, Johannes H. Smit, A. Smith, M. X. Sosa, T. Spector, A. Stančáková, Alice Stanton, K. Stirrups, H. Stringham, J. Sundstrom, A. Swift, A. Syvänen, E. Tai, Toshiko Tanaka, Kirill V Tarasov, A. Teumer, U. Thorsteinsdóttir, Martin D. Tobin, E. Tremoli, A. Uitterlinden, M. Uusitupa, Ahmad Vaez, Dhananjay Vaidya, Cornelia M. van Duijn, Erik P A van Iperen, R. Vasan, G. Verwoert, J. Virtamo, V. Vitart, B. Voight, P. Vollenweider, A. Wagner, L. Wain, N. Wareham, H. Watkins, A. Weder, H. Westra, R. Wilks, T. Wilsgaard, James F. Wilson, Tien Y. Wong, Tsun-Po Yang, Jie Yao, L. Yengo, Weihua Zhang, Jinghua Zhao, Xiaofeng Zhu, P. Bovet, Richard S. Cooper, K. Mohlke, D. Saleheen, Jong-Young Lee, P. Elliott, H. Gierman, C. Willer, L. Franke, G. K. Hovingh, Kent D. Taylor, G. Dedoussis, P. Sever, A. Wong, L. Lind, T. Assimes, I. Njølstad, Peter E. H. Schwarz, C. Langenberg, H. Snieder, M. Caulfield, O. Melander, M. Laakso, J. Saltevo, R. Rauramaa, J. Tuomilehto, E. Ingelsson, T. Lehtimäki, K. Hveem, W. Palmas, W. März, M. Kumari, V. Salomaa, Y. I. Chen, J. Rotter, P. Froguel, M. Jarvelin, E. Lakatta, K. Kuulasmaa, Paul W. Franks, A. Hamsten, H. Wichmann, Colin N. A. Palmer, K. Stefansson, P. Ridker, Ruth J. F. Loos, A. Chakravarti, P. Deloukas, Andrew P. Morris, C. Newton‐Cheh, P. Munroe +312 moresemanticscholar +1 more sourceAssociations of Stroke With Risk of Epilepsy: Results From the Atherosclerosis Risk in Communities (ARIC) Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To estimate the risk of epilepsy associated with stroke in a community‐based cohort, with consideration of stroke type, number, and severity. Methods
Data from 15,100 Atherosclerosis Risk in Communities (ARIC) Study participants without stroke at baseline (1987–1989) were analyzed through 12/31/2022.Jiping Zhou, Asma A. Ladak, Connor A. Law, Michelle C. Johansen, Anny Reyes, Silvia Koton, Sean Kelly, Jeubin Huang, Kamakshi Lakshminarayan, Rebecca F. Gottesman, Emily Johnson, Andrea L. C. Schneider +11 morewiley +1 more sourceRepeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods
We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...Laura Llansó, Igor Stevanovski, Germán Morís, Roger Collet‐Vidiella, Alba Segarra‐Casas, Lidia González‐Quereda, Benjamín Rodríguez‐Santiago, Pia Gallano, Rodrigo Alvarez, Ana Vesperinas, Rosa Blanco, Beatriz San‐Millán, Carmen Navarro, Isabel Illa, Gianina Ravenscroft, Ira W. Deveson, Eduard Gallardo, Montse Olivé +17 morewiley +1 more sourceBrachial-ankle PWV for predicting clinical outcomes in patients with acute stroke
Blood Pressure, 2017 Background: Although brachial-ankle pulse wave velocity (baPWV) is well-known for predicting the cardiovascular mortality and morbidity, its anticipated value is not demonstrated well concerning acute stroke.Kye Taek Ahn, Jin-Ok Jeong, Seon-Ah Jin, Mijoo Kim, Jin Kyung Oh, Ung-lim Choi, Seok-Woo Seong, Jun Hyung Kim, Si Wan Choi, Hye Seon Jeong, Hee-Jung Song, Jei Kim, In-Whan Seong +12 moredoaj +1 more sourceNOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...Han‐Lin Chiang, Kang‐Yang Jih, Cheng‐Tsung Hsiao, Fu‐Pang Chang, Justus Chunyu Chen, Yi‐Chu Liao, Yih‐Ru Wu, Yi‐Chung Lee +7 morewiley +1 more sourceThe effects of baroreflex activation therapy on blood pressure and sympathetic function in patients with refractory hypertension: the rationale and design of the Nordic BAT study*
Blood Pressure, 2017 Objective: To explore the effects of baroreflex activation therapy (BAT) on hypertension in patients with treatment resistant or refractory hypertension.Daniel Gordin, Fadl Elmula M. Fadl Elmula, Bert Andersson, Anders Gottsäter, Johan Elf, Thomas Kahan, Kent Lodberg Christensen, Pirkka Vikatmaa, Leena Vikatmaa, Thomas Bastholm Olesen, Per-Henrik Groop, Michael Hecht Olsen, Ilkka Tikkanen +12 moredoaj +1 more sourceCentral Dysmyelination in SSADH‐Deficient Humans and Mice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives
Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl +11 morewiley +1 more sourceOffice blood pressure measurements with oscillometric devices in adolescents: a comparison with home blood pressure
Blood Pressure, 2017 Purpose: Compare multiple in office BP measurements in adolescents using an oscillometric device with out-of-office blood pressure measurements (home blood pressure monitoring – HBPM).Thiago Veiga Jardim, Thomas A. Gaziano, Flávia Miquetichuc Nascente, Carolina de Souza Carneiro, Polyana Morais, Vanessa Roriz, Karla Lorena Mendonça, Thaís Inácio Rolim Póvoa, Weimar Kunz Sebba Barroso, Ana Luiza Lima Sousa, Paulo César Veiga Jardim +10 moredoaj +1 more source
