Results 81 to 90 of about 10,428,884 (381)

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

open access: yesNature Genetics, 2018
In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis.
Ayush Giri   +101 more
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

BLOOD PRESSURE LEVELS AND TRENDS OF OBESITY IN HYPERTENSIVE PATIENTS VERSUS HEALTH INDIVIDUALS: ISFAHAN 1991-2001

open access: yesARYA Atherosclerosis, 2010
Introduction: Obesity is an independent risk factor for cardiovascular disease. Several clinical studies have shown that blood pressure decreases significantly with reduction of body weight.
Alireza Khosravi   +2 more
doaj  

Ear oximeter-transducer monitors four physiological responses [PDF]

open access: yes, 1972
Device monitors blood oxygen saturation, blood pressure, pulse rate, and pulse-pressure curve during conditions of high stress in simulated space ...
Smith, J. R., Jr.
core   +1 more source

Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

open access: yesBritish medical journal, 2009
Objectives To determine the quantitative efficacy of different classes of blood pressure lowering drugs in preventing coronary heart disease (CHD) and stroke, and who should receive treatment. Design Meta-analysis. Data source Medline (1966-2007).
M. Law, J. Morris, N. Wald
semanticscholar   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Cuff-Less Methods for Blood Pressure Telemonitoring. [PDF]

open access: yes, 2019
Blood pressure telemonitoring (BPT) is a telemedicine strategy that uses a patient\u27s self-measured blood pressure (BP) and transmits this information to healthcare providers, typically over the internet.
Bard, Dylan M.   +2 more
core   +2 more sources

Blood pressure variability: clinical relevance and application

open access: yesThe Journal of Clinical Hypertension, 2018
Blood pressure variability is an entity that characterizes the continuous and dynamic fluctuations that occur in blood pressure levels throughout a lifetime.
G. Parati   +3 more
semanticscholar   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Central hemodynamics in relation to blood lead in young men prior to chronic occupational exposure

open access: yesBlood Pressure, 2019
Background: Aortic pulse wave velocity (aPWV) predicts cardiovascular complications, but the association of central arterial properties with blood lead level (BL) is poorly documented.
Cai-Guo Yu   +10 more
doaj   +1 more source

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